{"title":"艰难梭状芽胞杆菌感染:针对不受欢迎和持续的威胁","authors":"Hann Moir","doi":"10.33590/emjmicrobiolinfectdis/10301279","DOIUrl":null,"url":null,"abstract":"An integrated symposium, with an esteemed panel of experts, discussed the burden and treatment approaches for Clostridioides difficile infection (CDI). The session took place on 17th April 2023 as part of the 33rd European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 2023 in Copenhagen, Denmark. The session was co-chaired by Mark Wilcox, Head of Microbiology Research & Development and Infection Lead at Leeds Teaching Hospitals NHS Trust, UK, and Professor of Medical Microbiology at the University of Leeds, UK; and Anne Gonzales-Luna, Assistant Professor at the University of Houston College of Pharmacy, Texas, USA. Sarah Tschudin-Sutter, Professor and Head Division of Hospital Epidemiology at the University Hospital Basel, Switzerland, explored the changing landscape for CDI, including the epidemiology and surveillance of infection, and approaches to diagnosis. John Coia, Professor Emeritus at the Institute of Regional Health Research, University of South Denmark, and Honorary Research Fellow at Glasgow University, UK; and Esther Calbo, Professor and Head of Infectious Disease at the Hospital Universitari Mútua de Terrassa, Spain, gave an overview of the burden of recurrent CDI, dysbiosis in CDI, and the role in recurrent CDI, mortality risk, and the importance of targeting recurrence. Calbo also presented an interactive case study that allowed audience members to engage and review the patient case presented. The faculty panel explored with the audience how to approach assessment and treatment to achieve the best outcome for the patient case. Benoît Guery, Associate Professor Infectious Disease at the Centre Hospitalier Universitaire Vaudois, Switzerland, presented data from the EXTEND study, which explored extended-pulse dosing regimens of antibiotics (fidaxomicin) in CDI.","PeriodicalId":72900,"journal":{"name":"EMJ. Microbiology & infectious diseases","volume":"94 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Clostridioides difficile Infection: Targeting an Unwelcome and Persistent Threat\",\"authors\":\"Hann Moir\",\"doi\":\"10.33590/emjmicrobiolinfectdis/10301279\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"An integrated symposium, with an esteemed panel of experts, discussed the burden and treatment approaches for Clostridioides difficile infection (CDI). 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引用次数: 0
摘要
一个由专家组成的综合研讨会讨论了艰难梭菌感染(CDI)的负担和治疗方法。该会议于2023年4月17日在丹麦哥本哈根举行,是2023年第33届欧洲临床微生物学和传染病大会(ECCMID)的一部分。会议由微生物研究和amp负责人Mark Wilcox共同主持;英国利兹教学医院NHS信托的发展和感染负责人,英国利兹大学医学微生物学教授;Anne Gonzales-Luna,美国德克萨斯州休斯顿大学药学院助理教授。瑞士巴塞尔大学医院流行病学教授兼主任Sarah Tschudin-Sutter探讨了CDI不断变化的情况,包括流行病学和感染监测以及诊断方法。南丹麦大学区域卫生研究所名誉教授、英国格拉斯哥大学名誉研究员John Coia;西班牙特拉萨大学医院(Mútua de Terrassa)教授兼传染病科主任Esther Calbo概述了复发性CDI的负担、CDI的生态失调、在复发性CDI中的作用、死亡风险以及靶向复发的重要性。Calbo还介绍了一个交互式案例研究,允许观众参与并回顾所介绍的患者病例。教师小组与听众探讨了如何进行评估和治疗以达到患者病例的最佳结果。瑞士Vaudois大学医院中心传染病学副教授beno t Guery介绍了EXTEND研究的数据,该研究探索了CDI中抗生素(非达霉素)的延长脉冲给药方案。
Clostridioides difficile Infection: Targeting an Unwelcome and Persistent Threat
An integrated symposium, with an esteemed panel of experts, discussed the burden and treatment approaches for Clostridioides difficile infection (CDI). The session took place on 17th April 2023 as part of the 33rd European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 2023 in Copenhagen, Denmark. The session was co-chaired by Mark Wilcox, Head of Microbiology Research & Development and Infection Lead at Leeds Teaching Hospitals NHS Trust, UK, and Professor of Medical Microbiology at the University of Leeds, UK; and Anne Gonzales-Luna, Assistant Professor at the University of Houston College of Pharmacy, Texas, USA. Sarah Tschudin-Sutter, Professor and Head Division of Hospital Epidemiology at the University Hospital Basel, Switzerland, explored the changing landscape for CDI, including the epidemiology and surveillance of infection, and approaches to diagnosis. John Coia, Professor Emeritus at the Institute of Regional Health Research, University of South Denmark, and Honorary Research Fellow at Glasgow University, UK; and Esther Calbo, Professor and Head of Infectious Disease at the Hospital Universitari Mútua de Terrassa, Spain, gave an overview of the burden of recurrent CDI, dysbiosis in CDI, and the role in recurrent CDI, mortality risk, and the importance of targeting recurrence. Calbo also presented an interactive case study that allowed audience members to engage and review the patient case presented. The faculty panel explored with the audience how to approach assessment and treatment to achieve the best outcome for the patient case. Benoît Guery, Associate Professor Infectious Disease at the Centre Hospitalier Universitaire Vaudois, Switzerland, presented data from the EXTEND study, which explored extended-pulse dosing regimens of antibiotics (fidaxomicin) in CDI.