胡椒碱的治疗潜力:综述

IF 0.7 Q4 CHEMISTRY, MEDICINAL

Natural Products Journal Pub Date : 2023-10-04 DOI:10.2174/0122103155273860230928071249

Sonia Singh, Arpit Shukla

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引用次数: 0

摘要

摘要:胡椒碱是一种从黑胡椒中提取的生物碱，具有多种药理特性和潜在的治疗应用价值。胡椒碱的含量因胡椒植物而异，黑胡椒的含量在2%到7.4%之间。胡椒碱具有显著的生物学特性，包括抗氧化、抗炎、抗菌、抗癌、神经保护和肝脏保护。它能够影响许多信号通路和涉及疾病发展的生物学靶点，这是这些功能的原因。研究表明胡椒碱具有很高的抗氧化活性，有助于减少氧化应激和防止细胞损伤。已证实其抗炎作用可抑制促炎介质的产生，从而缓解炎症相关疾病。本文综述了胡椒碱的医学和健康促进作用，并提出了其在健康促进和疾病预防中的作用机制。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Therapeutic Potential of Piperine: A Comprehensive Review

Abstract: Piperine, an alkaloid from black pepper, has demonstrated diverse pharmacological properties and potential therapeutic applications. Piperine content varies with the pepper plant and ranges from 2 to 7.4% in black pepper. Piperine possesses remarkable biological properties, including antioxidant, anti-inflammatory, antibacterial, anticancer, neuroprotective, and hepatoprotective qualities. Its ability to affect numerous signaling pathways and biological targets implicated in disease development is responsible for these functions. Studies have shown piperine to have high antioxidant activity, which aids in reducing oxidative stress and preventing cellular damage. It has been established that its anti-inflammatory effects suppress the generation of pro-inflammatory mediators, thereby relieving inflammation-related diseases. This review emphasizes and examines piperine's medical and health-promoting benefits and proposed mechanisms of action in health promotion and illness prevention.

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来源期刊

Natural Products Journal CHEMISTRY, MEDICINAL-

CiteScore

1.70

自引率

0.00%

发文量

期刊介绍： The Natural Products Journal a peer reviewed journal, aims to publish all the latest and outstanding developments in natural products. The Natural Products Journal publishes original research articles, full-length/mini reviews, letters and guest edited issues on all aspects of research and development in the field including: isolation, purification, structure elucidation, synthesis and bioactivity of chemical compounds found in nature.