荆紫荆花乙醇提取物的植物药理研究

Sumanta Sen, Atal B. Singh, Jyotirmaya Sahoo, Alok K. Moharana, Nalini K. Sahoo, Madhusmita Sahu
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引用次数: 0

摘要

紫荆是豆科被子植物的一种,原产于南亚和东南亚、中国南部、缅甸、印度、尼泊尔、巴基斯坦和斯里兰卡。常见的名称包括B. acuminata,山乌木,骆驼脚树,kachnar和蝴蝶灰。被子植物是热带地区常见的药用植物,具有广泛的应用价值。自古以来,花、芽、茎、根、树皮、种子和叶子就被用来治疗许多疾病。非甾体抗炎药是目前使用的最重要的药物之一,一些临床问题需要长期使用。由于长期使用,副作用,特别是胃溃疡,可使患者的临床症状恶化。所以有必要使用止痛药,但它与问题无关,即使是长期使用。文献表明,对这种植物进行了大量的分析工作,但没有一项研究评估过它的镇痛和抗炎作用。制备水乙醇提取物,并在动物模型上评价其镇痛、抗炎和解热作用。结果表明,与原料药相比,200 mg/kg剂量的花提取物具有明显的镇痛、抗炎和解热作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Phyto-Pharmacological Investigation of Ethanolic Extract of Flowers of Bauhinia acuminata
Bauhinia acuminata is a type of angiosperm in the Fabaceae family, native to South and Southeast Asia, South China, Burma, India, Nepal, Pakistan, and Sri Lanka. The common names include B. acuminata, mountain ebony, camel’s foot tree, kachnar, and butterfly ash. Angiosperm tree could be widely used as a medicinal plant common in tropical regions. Flowers, buds, stems, roots, bark, seeds, and leaves have been used to treat many ailments since ancient times. NSAIDs are one of the most important classes of drugs used today, and several clinical problems require long-term use. As a result of long-term use, side effects, especially stomach ulcers, can worsen the patient’s clinical symptoms. So there is a requirement to go for painkillers, but it is not related to problems even with chronic use. The literature says that a lot of analytical work has been done on this plant, but none of it has been evaluated for its analgesic and anti-inflammatory effects. An aqueous ethanolic extract was prepared and its analgesic, anti-inflammatory, and antipyretic effects were evaluated in animal models. The results showed that the flower extract at 200 mg/kg dose had significant analgesic, anti-inflammatory, and antipyretic effects compared to the medicinal active drugs.
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