{"title":"互花千层、千叶阿喀琉木和樟脑阴道栓剂抑菌活性的比较研究","authors":"Merima Ibišević, Saša Pilipović, Darja Husejnagić, Fadila Malohodžić, Alma Kulanić, Lejla Mustafić, Ermina Cilović Kozarević, Emir Horozić, Enida Karić","doi":"10.51558/2232-7568.2023.16.1.1","DOIUrl":null,"url":null,"abstract":"Vaginal inflammation represents a heterogeneous group of disorders caused by infection, inflammation, or disruption of vaginal microflora. The most common causes of vaginal infection are Staphylococcus aureus, Enterococcus faecalis, Streptococcus agalactiae, Escherichia coliand Candida albicans. Antibiotic resistance is a major global problem, which can be mitigated by using natural antimicrobial substances such as essential oils. Each essential oil has an extremely complex composition (some essential oilshave over 200 components), which prevents microorganisms from developing resistance. Therefore, essential oils retain their effects.The aim of our study was to investigate antibacterial activity Melaleuca alternifolia, Achillea millefoliumand Cinnamomumcamphoravaginal suppositories, and see which essential oil has the strongest potential to be used as active ingredient for vaginal infections.The antimicrobial activity of the vaginal suppositories was examined using the disk diffusion method. Standard bacterial strains were used for the ATCC collection: Staphylococcus aureus (S. aureus) ATCC 25923, Enterococcus faecalis (E. faecalis)ATCC 51299, Escherichia coli (E. coli)ATCC 25922, Candida albicans (C. albicans)ATCC 10231.The results showed that Melaleuca alternifolia essential oil has an antimicrobial effect on all tested strains, with the strongest effect on Candida albicans(ZI 22.7 mm). Achillea millefoliumessential oil had no effect on Enterococcus faecalis, whereas Cinnamomum camphoraessential oil did not show zones of inhibition of Candida albicans.KEYWORDS:vaginal suppository, Melaleuca alternifolia, Achillea millefolium, Cinnamomum camphora,antimicrobial activity","PeriodicalId":43089,"journal":{"name":"Acta Technologica Agriculturae","volume":"127 1","pages":"0"},"PeriodicalIF":1.3000,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"ACOMPARATIVE STUDY OF ANTIMICROBIAL ACTIVITY OF MELALEUCA ALTERNIFOLIA,ACHILLEA MILLEFOLIUMAND CINNNAMOMUM CAMPHORAVAGINAL SUPPOSITORIES\",\"authors\":\"Merima Ibišević, Saša Pilipović, Darja Husejnagić, Fadila Malohodžić, Alma Kulanić, Lejla Mustafić, Ermina Cilović Kozarević, Emir Horozić, Enida Karić\",\"doi\":\"10.51558/2232-7568.2023.16.1.1\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Vaginal inflammation represents a heterogeneous group of disorders caused by infection, inflammation, or disruption of vaginal microflora. The most common causes of vaginal infection are Staphylococcus aureus, Enterococcus faecalis, Streptococcus agalactiae, Escherichia coliand Candida albicans. Antibiotic resistance is a major global problem, which can be mitigated by using natural antimicrobial substances such as essential oils. Each essential oil has an extremely complex composition (some essential oilshave over 200 components), which prevents microorganisms from developing resistance. Therefore, essential oils retain their effects.The aim of our study was to investigate antibacterial activity Melaleuca alternifolia, Achillea millefoliumand Cinnamomumcamphoravaginal suppositories, and see which essential oil has the strongest potential to be used as active ingredient for vaginal infections.The antimicrobial activity of the vaginal suppositories was examined using the disk diffusion method. Standard bacterial strains were used for the ATCC collection: Staphylococcus aureus (S. aureus) ATCC 25923, Enterococcus faecalis (E. faecalis)ATCC 51299, Escherichia coli (E. coli)ATCC 25922, Candida albicans (C. albicans)ATCC 10231.The results showed that Melaleuca alternifolia essential oil has an antimicrobial effect on all tested strains, with the strongest effect on Candida albicans(ZI 22.7 mm). Achillea millefoliumessential oil had no effect on Enterococcus faecalis, whereas Cinnamomum camphoraessential oil did not show zones of inhibition of Candida albicans.KEYWORDS:vaginal suppository, Melaleuca alternifolia, Achillea millefolium, Cinnamomum camphora,antimicrobial activity\",\"PeriodicalId\":43089,\"journal\":{\"name\":\"Acta Technologica Agriculturae\",\"volume\":\"127 1\",\"pages\":\"0\"},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2023-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta Technologica Agriculturae\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.51558/2232-7568.2023.16.1.1\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"AGRICULTURE, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta Technologica Agriculturae","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.51558/2232-7568.2023.16.1.1","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"AGRICULTURE, MULTIDISCIPLINARY","Score":null,"Total":0}
ACOMPARATIVE STUDY OF ANTIMICROBIAL ACTIVITY OF MELALEUCA ALTERNIFOLIA,ACHILLEA MILLEFOLIUMAND CINNNAMOMUM CAMPHORAVAGINAL SUPPOSITORIES
Vaginal inflammation represents a heterogeneous group of disorders caused by infection, inflammation, or disruption of vaginal microflora. The most common causes of vaginal infection are Staphylococcus aureus, Enterococcus faecalis, Streptococcus agalactiae, Escherichia coliand Candida albicans. Antibiotic resistance is a major global problem, which can be mitigated by using natural antimicrobial substances such as essential oils. Each essential oil has an extremely complex composition (some essential oilshave over 200 components), which prevents microorganisms from developing resistance. Therefore, essential oils retain their effects.The aim of our study was to investigate antibacterial activity Melaleuca alternifolia, Achillea millefoliumand Cinnamomumcamphoravaginal suppositories, and see which essential oil has the strongest potential to be used as active ingredient for vaginal infections.The antimicrobial activity of the vaginal suppositories was examined using the disk diffusion method. Standard bacterial strains were used for the ATCC collection: Staphylococcus aureus (S. aureus) ATCC 25923, Enterococcus faecalis (E. faecalis)ATCC 51299, Escherichia coli (E. coli)ATCC 25922, Candida albicans (C. albicans)ATCC 10231.The results showed that Melaleuca alternifolia essential oil has an antimicrobial effect on all tested strains, with the strongest effect on Candida albicans(ZI 22.7 mm). Achillea millefoliumessential oil had no effect on Enterococcus faecalis, whereas Cinnamomum camphoraessential oil did not show zones of inhibition of Candida albicans.KEYWORDS:vaginal suppository, Melaleuca alternifolia, Achillea millefolium, Cinnamomum camphora,antimicrobial activity
期刊介绍:
Acta Technologica Agriculturae is an international scientific double-blind peer reviewed journal focused on agricultural engineering. The journal is multidisciplinary and publishes original research and review papers in engineering, agricultural and biological sciences, and materials science. Aims and Scope Areas of interest include but are not limited to: agricultural and biosystems engineering; machines and mechanization of agricultural production; information and electrical technologies; agro-product and food processing engineering; physical, chemical and biological changes in the soil caused by tillage and field traffic, soil working machinery and terramechanics; renewable energy sources and bioenergy; rural buildings; related issues from applied physics and chemistry, ecology, economy and energy.