牙科实践在肿瘤治疗中的重要性:一个与乳腺癌相关的病例报告

Iandra Luah Souza MAIA, Rosany Larissa Brito de OLIVEIRA, Ellen Maiany Ribeiro SANTANA, Paula Patrícia Santos SANTOS, Álvaro Bezerra CARDOSO
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引用次数: 0

摘要

在巴西,预计2020年至2022年间新发癌症病例数为62.5万例,最常见的癌症主要是皮肤(非黑色素瘤),其次是乳腺癌、前列腺癌、结肠癌和直肠癌。虽然乳腺癌的死亡率仍然很高,但由于早期诊断的增加和抗癌治疗的发展,乳腺癌预后良好。建议的治疗可以单独进行,也可以与切除手术、放疗、化疗和/或激素替代相结合。化疗产生广泛的免疫抑制,影响健康和改变的细胞,治疗的细胞毒性是一个重要的影响,可引起口腔黏膜病变。严重程度与化疗药物的类型、治疗时间、使用的剂量和个体的年龄有关。此外,化疗可能会加剧个人已有的疾病,并在治疗期间引起更大的不适。因此,在抗癌治疗之前、期间和之后监测口腔健康是必不可少的。本工作的目的是报告一个临床病例的牙科急诊患者后,阿霉素-环磷酰胺-紫杉醇(ACTdd)治疗乳腺癌的第一个周期。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The importance of dental practice in oncological treatment: a case report associated with breast cancer
ABSTRACT In Brazil, the estimated number of new cancer cases between 2020 and 2022 is 625 thousand, and the most prevalent carcinomas are primarily skin (non-melanoma), followed by those of the breast, prostate, colon, and rectum. Although breast carcinoma still has a high mortality rate, it has a good prognosis due to the increase in early diagnosis and the evolution of anticancer treatments. The proposed treatment can be isolated or associated with resective surgery, radiotherapy, chemotherapy, and/or hormone replacement. Chemotherapy generates extensive immunosuppression and affects both healthy and altered cells, and the cytotoxicity of the treatment is an important effect that can cause lesions on the oral mucosa. Severity is related to the type of chemotherapeutic agent, treatment time, the dose used, and the individual’s age. Additionally, chemotherapy treatment can exacerbate preexisting conditions in the individual and cause greater discomfort during treatment. Therefore, monitoring oral health before, during, and after anticancer therapy is essential. The objective of this work is to report a clinical case of dental emergency in a patient after the first cycle of doxorubicin- cyclophosphamide-paclitaxel (ACTdd) to treat breast cancer.
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