{"title":"[IL-2在转移性颈淋巴结周围注射的影响]。","authors":"H Ogasawara, N Takeda, N Takeda, T Kumoi","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Six patients with squamous cell carcinoma of head and neck were treated with injection of interleukin-2 (IL-2) around the metastatic cervical lymphnodes. Lymphokine activated killer (LAK) activity in peripheral blood in administration of IL-2 showed a significant high of 13.2% at effector/target (E/T) ratio 13 compared with non-administration of IL-2 showed 4.3%. LAK activity in cervical non-metastatic lymphnodes in 6 cases of administration of IL-2 showed a significant high of 23.0% at E/T ratio 50 compared with 3 cases of non-administration of IL-2 which showed 3.7%. In the 2 evaluable courses given in patients a partial response was obtained in one case.</p>","PeriodicalId":76232,"journal":{"name":"Nihon Gan Chiryo Gakkai shi","volume":"25 6","pages":"1119-22"},"PeriodicalIF":0.0000,"publicationDate":"1990-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[The effect of IL-2 injection around the metastatic cervical lymphnode].\",\"authors\":\"H Ogasawara, N Takeda, N Takeda, T Kumoi\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Six patients with squamous cell carcinoma of head and neck were treated with injection of interleukin-2 (IL-2) around the metastatic cervical lymphnodes. Lymphokine activated killer (LAK) activity in peripheral blood in administration of IL-2 showed a significant high of 13.2% at effector/target (E/T) ratio 13 compared with non-administration of IL-2 showed 4.3%. LAK activity in cervical non-metastatic lymphnodes in 6 cases of administration of IL-2 showed a significant high of 23.0% at E/T ratio 50 compared with 3 cases of non-administration of IL-2 which showed 3.7%. In the 2 evaluable courses given in patients a partial response was obtained in one case.</p>\",\"PeriodicalId\":76232,\"journal\":{\"name\":\"Nihon Gan Chiryo Gakkai shi\",\"volume\":\"25 6\",\"pages\":\"1119-22\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1990-06-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nihon Gan Chiryo Gakkai shi\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nihon Gan Chiryo Gakkai shi","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[The effect of IL-2 injection around the metastatic cervical lymphnode].
Six patients with squamous cell carcinoma of head and neck were treated with injection of interleukin-2 (IL-2) around the metastatic cervical lymphnodes. Lymphokine activated killer (LAK) activity in peripheral blood in administration of IL-2 showed a significant high of 13.2% at effector/target (E/T) ratio 13 compared with non-administration of IL-2 showed 4.3%. LAK activity in cervical non-metastatic lymphnodes in 6 cases of administration of IL-2 showed a significant high of 23.0% at E/T ratio 50 compared with 3 cases of non-administration of IL-2 which showed 3.7%. In the 2 evaluable courses given in patients a partial response was obtained in one case.
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