一只成年杂交犬胰岛素瘤的临床病理和免疫组织化学特征

Q4 Veterinary
Isabeli Joaquim Contel, Pedro Pol Ximenes, Fernando Carmona Dinau, Fernanda Barthelson Carvalho de Moura, Giovanna Gati de Souza, Iolanda Simões Braga, Isadora Fernanda Pelaquim, Rafael Torres, Noeme Sousa Rocha
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引用次数: 0

摘要

犬胰岛素瘤是一种常见的具有高转移能力的非特异性肿瘤。它的流行病学、诊断和治疗都有很好的描述。然而,其长期预后被认为很差。我们报告一例罕见的胰岛素瘤病例,发生在一只小型混血成年犬身上,表现为绕圈行走、癫痫发作、虚弱、精神状态抑郁和低血糖。葡萄糖持续输注、安定和苯巴比妥用于稳定血糖和控制惊厥。血液检查、细针穿刺细胞学检查、超声和放射学检查以及组织学和免疫组织化学分析证实了胰岛素瘤的诊断,强调了将其作为小型犬种和年轻动物的鉴别诊断的相关性。此外,由于狗具有相同的特征,因此可以将其视为人类胰岛素瘤研究的实验动物模型。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinicopathological and immunohistochemical features of insulinoma in an adult mixed breed dog
Canine insulinoma is a common non-specific neoplasm with high metastasizing ability. Its epidemiology, diagnosis, and treatment are well described. However, its long-term prognosis is considered poor. We report a rare case of insulinoma in a small-size, mixed-breed adult dog, which presented with a circling walk, seizures, weakness, depressed mental state, and hypoglycemia. Glucose continuous rate infusion, diazepam, and phenobarbital were initiated to stabilize the glycemia and control the convulsion. Blood tests, fine needle aspiration cytology, ultrasound and radiological tests, and histology and immunohistochemical analysis confirmed the diagnosis of insulinoma, emphasizing the relevance of considering it as a differential diagnosis for small canine breeds and younger animals. Further, dogs can be regarded as an experimental animal model for human insulinoma research as they share characteristics.
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来源期刊
Brazilian Journal of Veterinary Pathology
Brazilian Journal of Veterinary Pathology Veterinary-Veterinary (miscellaneous)
CiteScore
0.60
自引率
0.00%
发文量
24
期刊介绍: The Brazilian Journal of Veterinary Pathology is the official electronic periodical of the Brazilian Association of Veterinary Pathology. The purpose of the BJVP is to publish original full papers, short communications, case reports, letters, reviews (by invited experts) and abstracts of scientific meetings. The preferable subjects is natural and experimental pathology. All the articles are submitted to scientific reviewers.
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