abcb4突变患者的综合胆汁酸谱及牛磺酸偶联的3α，6α，7α，12α-四羟化胆汁酸在胆汁淤积症中的预后作用

IF 3.1 3区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY

Journal of Clinical and Translational Hepatology Pub Date : 2023-09-15 DOI:10.14218/jcth.2023.00095

Teng Liu, Ren-Xue Wang, Jun Han, Zhong-Die Li, Jonathan A. Sheps, Li-Juan Zheng, Xiao-Xiao Xu, Victor Ling, Jian-She Wang

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引用次数: 0

摘要

背景和目的我们询问全面的胆汁酸谱分析是否可以为abcb4突变患者的生理病理提供见解，并评估牛磺酸偶联四羟基化胆汁酸(牛磺酸- thba)在胆汁淤积症中的预后价值。

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Comprehensive Bile Acid Profiling of ABCB4-mutated Patients and the Prognostic Role of Taurine-conjugated 3α,6α,7α,12α-Tetrahydroxylated Bile Acid in Cholestasis

Background and AimsWe asked if comprehensive bile acid profiling could provide insights into the physiopathology of ABCB4-mutated patients and evaluated the prognostic value of taurine-conjugated tetrahydroxylated bile acid (tauro-THBA) in cholestasis.

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来源期刊

Journal of Clinical and Translational Hepatology GASTROENTEROLOGY & HEPATOLOGY-

CiteScore

6.40

自引率

2.80%

发文量

496