前列腺癌患者神经节生理性[68Ga]Ga-PSMA-11和[18F]PSMA-1007摄取的个体内比较:回顾性单中心分析

IF 1 4区医学 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Nuklearmedizin-nuclear Medicine Pub Date : 2023-03-30 DOI:10.1055/s-0043-1766379

E. Novruzov, D. Schmitt, K. Mattes-György, M. Beu, J. M. Henke, C. Antke, J. Cardinale, G. Niegisch, L. Schimmöller, F. L. Giesel, E. Mamlins

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引用次数: 0

摘要

几项研究表明，在PSMA PET成像中，良性发现的检出率相对较高，尤其是神经节。到目前为止，还没有研究直接比较[68Ga]Ga-PSMA-11和[18F]PSMA-1007在个体内的神经节摄取，并分析不同的检出率及其潜在的分子和物理机制。通过这项单中心回顾性研究，我们试图评估个体内不同PSMA配体的生理神经节摄取。

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Intraindividual Comparison of Physiologic [68Ga]Ga-PSMA-11 and [18F]PSMA-1007 Uptake in Ganglia in Patients with Prostate Cancer: a retrospective, monocentric analysis

Ziel/Aim Several studies indicate a relatively high rate of detection of benign findings, in particular ganglia, in PSMA PET imaging. To date, no studies have directly compared [68Ga]Ga-PSMA-11 and [18F]PSMA-1007 ganglionic uptake intraindividually and analyzed the different detection rates and underlying molecular and physical mechanisms. With this monocentric retrospective study, we sought to evaluate the intraindividual physiological ganglion uptake of different PSMA ligands.

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来源期刊

Nuklearmedizin-nuclear Medicine 医学-核医学

CiteScore

1.70

自引率

13.30%

发文量

267

审稿时长

>12 weeks

期刊介绍： Als Standes- und Fachorgan (Organ von Deutscher Gesellschaft für Nuklearmedizin (DGN), Österreichischer Gesellschaft für Nuklearmedizin und Molekulare Bildgebung (ÖGN), Schweizerischer Gesellschaft für Nuklearmedizin (SGNM, SSNM)) von hohem wissenschaftlichen Anspruch befasst sich die CME-zertifizierte Nuklearmedizin/ NuclearMedicine mit Diagnostik und Therapie in der Nuklearmedizin und dem Strahlenschutz: Originalien, Übersichtsarbeiten, Referate und Kongressberichte stellen aktuelle Themen der Diagnose und Therapie dar. Ausführliche Berichte aus den DGN-Arbeitskreisen, Nachrichten aus Forschung und Industrie sowie Beschreibungen innovativer technischer Geräte, Einrichtungen und Systeme runden das Konzept ab. Die Abstracts der Jahrestagungen dreier europäischer Fachgesellschaften sind Bestandteil der Kongressausgaben. Nuklearmedizin erscheint regelmäßig mit sechs Ausgaben pro Jahr und richtet sich vor allem an Nuklearmediziner, Radiologen, Strahlentherapeuten, Medizinphysiker und Radiopharmazeuten.