IS/OS-Ellipsoid Zone Complex Anomaly of Benign Concentric Annular Macular Dystrophy

Aim: To report IS/OS-Ellipsoid zone complex anomaly of benign concentric annular macular dystrophy. Methods: A case of adult-onset macular dystrophy was observed with BCAMD associated with the IS/OS-Ellipsoid zone complex anomaly by CFP, OCT, en-face analysis, FA and FAF, etc. Results: CFP revealed concentric rings in the parafoveal area prominent and drusen in the macula of right eye and not concentric rings in the left eye. No concentric ring changes were observed in FA and FAF. En-face analysis found that the IS/OS-Ellipsoid complex was obviously abnormal. Although the left eye did not show the concentric ring-like changes in the CFP, but IS/OS-Ellipsoid complex was abnormal with semi-annular blotch-like dark areas. Conclusion: BCAMD is a rare macular dystrophy. En-face analysis found that the IS/OS-Ellipsoid complex was obviously abnormal.