Preparation of Manganese Phthalocyanine Nanoparticles by Laser Ablation in Liquid and Application to Bioimaging

In this study, nanoparticles of manganese phthalocyanine (MnPc) were synthesized through laser ablation in liquid. The MnPc powder was dispersed in deionized water using sonification, and the resulting suspension was irradiated with a Nd:YAG laser. The synthesized nanoparticles were characterized using various techniques including Scanning Electron Microscope (SEM), Dynamic Light Scattering (DLS), Ultraviolet-visible spectroscopy (UV-Vis), and zeta potential analysis. The SEM analysis revealed that the morphology of the nanoparticles was predominantly spherical particles. The DLS measurements showed that the secondary particle sizes decreased as the laser fluence increased. The UV-Vis spectroscopy results indicated an increase in absorbance at low laser fluence, followed by a decrease at high laser fluence. Additionally, the zeta potential analysis confirmed the dispersion stability of the nanoparticles. The photoacoustic signal generated by the nanoparticles exhibited an increase at low laser fluence and a decrease at high laser fluence. These results demonstrate the successful synthesis of MnPc nanoparticles using laser ablation in liquid. The obtained nanoparticles exhibited desirable morphological characteristics and showed potential for enhancing photoacoustic signals.