纳米给药系统在胃肠道肿瘤中的研究进展

IF 0.7 4区材料科学 Q3 Materials Science

Materials Express Pub Date : 2023-10-01 DOI:10.1166/mex.2023.2519

Xiaoqi Guan, Ke Zhang, Xianghuang Mei, Zhipeng He, Shi Su, Jingcheng Yang, Jiake Lv, Li Yuan, Xiao Duan, Wei Guo

{"title":"纳米给药系统在胃肠道肿瘤中的研究进展","authors":"Xiaoqi Guan, Ke Zhang, Xianghuang Mei, Zhipeng He, Shi Su, Jingcheng Yang, Jiake Lv, Li Yuan, Xiao Duan, Wei Guo","doi":"10.1166/mex.2023.2519","DOIUrl":null,"url":null,"abstract":"Gastrointestinal cancer is a major cancer type with a high incidence worldwide. In China, most patients with gastrointestinal tumors are diagnosed in the late stage and are unsuitable for surgery. Chemotherapy is the last treatment option for most advanced tumor patients. However, it always leads to severe side effects on the human body. The emergence of nano-carrier-based drug delivery can remarkably increase drug efficiency and avoid severe side effects in cancer patients. This article reviews the therapeutic application of nano-drug delivery systems (NDDSs) in gastrointestinal tumors in recent years, which is expected to improve the quality of life of advanced cancer patients and help develop more nano-drugs for gastrointestinal cancer patients.","PeriodicalId":18318,"journal":{"name":"Materials Express","volume":"25 1","pages":"0"},"PeriodicalIF":0.7000,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Recent progress of nano-drug delivery systems in gastrointestinal cancer\",\"authors\":\"Xiaoqi Guan, Ke Zhang, Xianghuang Mei, Zhipeng He, Shi Su, Jingcheng Yang, Jiake Lv, Li Yuan, Xiao Duan, Wei Guo\",\"doi\":\"10.1166/mex.2023.2519\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Gastrointestinal cancer is a major cancer type with a high incidence worldwide. In China, most patients with gastrointestinal tumors are diagnosed in the late stage and are unsuitable for surgery. Chemotherapy is the last treatment option for most advanced tumor patients. However, it always leads to severe side effects on the human body. The emergence of nano-carrier-based drug delivery can remarkably increase drug efficiency and avoid severe side effects in cancer patients. This article reviews the therapeutic application of nano-drug delivery systems (NDDSs) in gastrointestinal tumors in recent years, which is expected to improve the quality of life of advanced cancer patients and help develop more nano-drugs for gastrointestinal cancer patients.\",\"PeriodicalId\":18318,\"journal\":{\"name\":\"Materials Express\",\"volume\":\"25 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.7000,\"publicationDate\":\"2023-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Materials Express\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1166/mex.2023.2519\",\"RegionNum\":4,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Materials Science\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Materials Express","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1166/mex.2023.2519","RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Materials Science","Score":null,"Total":0}

引用次数: 0

摘要

胃肠癌是世界范围内发病率较高的主要癌症类型。在中国，大多数胃肠道肿瘤患者诊断为晚期，不适合手术。化疗是大多数晚期肿瘤患者最后的治疗选择。然而，它总是会对人体产生严重的副作用。纳米载体给药技术的出现，可以显著提高肿瘤患者的给药效率，避免严重的副作用。本文综述了近年来纳米药物递送系统(NDDSs)在胃肠道肿瘤中的治疗应用，以期改善晚期肿瘤患者的生活质量，为胃肠道肿瘤患者开发更多纳米药物提供参考。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Recent progress of nano-drug delivery systems in gastrointestinal cancer

Gastrointestinal cancer is a major cancer type with a high incidence worldwide. In China, most patients with gastrointestinal tumors are diagnosed in the late stage and are unsuitable for surgery. Chemotherapy is the last treatment option for most advanced tumor patients. However, it always leads to severe side effects on the human body. The emergence of nano-carrier-based drug delivery can remarkably increase drug efficiency and avoid severe side effects in cancer patients. This article reviews the therapeutic application of nano-drug delivery systems (NDDSs) in gastrointestinal tumors in recent years, which is expected to improve the quality of life of advanced cancer patients and help develop more nano-drugs for gastrointestinal cancer patients.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Materials Express NANOSCIENCE & NANOTECHNOLOGY-MATERIALS SCIENCE, MULTIDISCIPLINARY

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Information not localized