脉络膜上曲安奈德治疗难治性糖尿病黄斑水肿的疗效

Q4 Medicine
Muhammad Hannan Jamil, Aneeb Ashraf, Asmatullah Khan, Bilal Ashraf, Muhammad Bilal Afzal, Ferheen Shahbaz
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引用次数: 0

摘要

糖尿病视网膜病变患者中央视力恶化的最常见原因之一是糖尿病性黄斑水肿。脉络膜上注射为皮质类固醇的给药提供了一种新的方式,可能有各种好处。目的:观察曲安奈德经脉络膜上给药治疗难治性糖尿病黄斑水肿的疗效。方法:采用描述性病例系列研究,于2021年7月14日至2022年1月14日在拉合尔木尔坦路Layton Rahmatullah Benevolant Trust医院眼科进行。经医院伦理委员会批准,共选取符合入选标准的病例60例。所有注射均由一名外科医生进行,以避免任何相关的偏差。所有病例均使用30号1cc胰岛素注射器。结果:患者年龄30 ~ 70岁,平均年龄52.73±10.99岁。男性39例(65%),女性21例(35%)。1个月前后中心子野平均厚度分别为593.62±116.87µm和303.55±31.29µm, 1个月后中心子野平均厚度差异有统计学意义,p值< 0.001。矫正后1个月前平均视力为0.81±0.16,1个月后平均视力为0.45±0.03,矫正后1个月平均最佳视力低于矫正前平均视力,p值均小于0.001。结论:脉络膜上曲安奈德可有效控制糖尿病性黄斑水肿患者的中心亚野和最佳矫正视力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Outcome of Suprachoroidal Triamcinolone Acetonide in Resistant Diabetic Macular Edema
One of the most frequent cause of central vision deterioration in people with retinopathy due to diabetes is diabetic macular edema. Suprachoroidal injections offer a novel way of delivery for the administration of corticosteroids that may have various benefits. Objective: To observe outcome of triamcinolone acetonide given by suprachoroidal route for the treatment of resistant diabetic macular edema. Methods: A descriptive case series study which was carried out at Department of Ophthalmology, Layton Rahmatullah Benevolant Trust Hospital Multan Road Lahore from July 14, 2021 till Jan 14, 2022. A total of 60 cases meeting selection criteria was taken after taking approval from hospital ethical committee. All injections were given by a single surgeon to avoid any related bias. 30-gauge 1cc insulin syringe was used in all cases. Results: The study included patients aged between 30 and 70 years, and the average age was 52.73 ± 10.99 years. There were 39(65%) male with 21(35%) female cases. The average central subfield thickness before and after one month was 593.62 ± 116.87 µm and 303.55 ± 31.29 µm with statistically significantly less mean central subfield thickness after 1 month, p-value less than 0.001. The mean visual acuity after correction before and after one month was 0.81 ± 0.16 and 0.45 ± 0.03 respectively, with statistically significantly less mean optimally corrected visual acuity after 1 month, p-value less than 0.001. Conclusions: It was found that suprachoroidal triamcinolone acetonide is useful in managing the central subfield and optimally corrected visual acuity in resistant diabetic macular edema.
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来源期刊
Pakistan Journal of Medical & Health Sciences
Pakistan Journal of Medical & Health Sciences MEDICINE, GENERAL & INTERNAL-
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期刊介绍: Pakistan Journal of Medical and Health Sciences is an international biomedical journal from Pakistan. We publish materials of interest to the practitioners and scientists in the broad field of medicine. Articles describing original qualitative, quantitative, human/animal clinical or laboratory studies are considered for publication.
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