中枢性和外周性性早熟女孩的代谢组学研究

Q3 Pharmacology, Toxicology and Pharmaceutics

Fabad Journal of Pharmaceutical Sciences Pub Date : 2023-09-29 DOI:10.55262/fabadeczacilik.1344851

Aylin BALCI ÖZYURT, Tuba REÇBER, Emirhan NEMUTLU, Derya BULUŞ, Sedef KIR, Belma KOÇER GÜMÜŞEL, Pınar ERKEKOĞLU

{"title":"中枢性和外周性性早熟女孩的代谢组学研究","authors":"Aylin BALCI ÖZYURT, Tuba REÇBER, Emirhan NEMUTLU, Derya BULUŞ, Sedef KIR, Belma KOÇER GÜMÜŞEL, Pınar ERKEKOĞLU","doi":"10.55262/fabadeczacilik.1344851","DOIUrl":null,"url":null,"abstract":"Puberte prekoks (PP), kızlarda sekonder cinsel özelliklerin sekiz yaşından önce başlamasıdır. Hipotalamus hipofiz-gonad ekseninin erken aktivasyonu nedeniyle \"merkezi puberte prekoks (CPP)\" meydana gelir. \"Periferik puberte prekoks (PPP)\" hipotalamus-hipofiz-gonad (HPG) aksına bağlı olmayan daha nadir görülen farklı bir durumdur ve periferik nedenlere bağlıdır. Metabolomiks, küçük molekül metabolitlerinin (","PeriodicalId":36004,"journal":{"name":"Fabad Journal of Pharmaceutical Sciences","volume":"45 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Metabolomic Studies in Girls With Central and Peripheral Precocious Puberty\",\"authors\":\"Aylin BALCI ÖZYURT, Tuba REÇBER, Emirhan NEMUTLU, Derya BULUŞ, Sedef KIR, Belma KOÇER GÜMÜŞEL, Pınar ERKEKOĞLU\",\"doi\":\"10.55262/fabadeczacilik.1344851\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Puberte prekoks (PP), kızlarda sekonder cinsel özelliklerin sekiz yaşından önce başlamasıdır. Hipotalamus hipofiz-gonad ekseninin erken aktivasyonu nedeniyle \\\"merkezi puberte prekoks (CPP)\\\" meydana gelir. \\\"Periferik puberte prekoks (PPP)\\\" hipotalamus-hipofiz-gonad (HPG) aksına bağlı olmayan daha nadir görülen farklı bir durumdur ve periferik nedenlere bağlıdır. Metabolomiks, küçük molekül metabolitlerinin (\",\"PeriodicalId\":36004,\"journal\":{\"name\":\"Fabad Journal of Pharmaceutical Sciences\",\"volume\":\"45 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-09-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Fabad Journal of Pharmaceutical Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.55262/fabadeczacilik.1344851\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Pharmacology, Toxicology and Pharmaceutics\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Fabad Journal of Pharmaceutical Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.55262/fabadeczacilik.1344851","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Pharmacology, Toxicology and Pharmaceutics","Score":null,"Total":0}

引用次数: 0

摘要

青春期早熟（PP）是指女孩在 8 岁前开始出现第二性征。"中枢性性早熟（CPP）"是由于下丘脑-垂体-性腺轴的早期激活所致。"外周性性早熟（PPP）"是一种不同的、罕见的情况，它不依赖于下丘脑-垂体-性腺轴，而是由外周原因引起的。代谢组学（Metabolomics）是一种分析小分子代谢物（如蛋白质、脂肪和碳水化合物）的方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Metabolomic Studies in Girls With Central and Peripheral Precocious Puberty

Puberte prekoks (PP), kızlarda sekonder cinsel özelliklerin sekiz yaşından önce başlamasıdır. Hipotalamus hipofiz-gonad ekseninin erken aktivasyonu nedeniyle "merkezi puberte prekoks (CPP)" meydana gelir. "Periferik puberte prekoks (PPP)" hipotalamus-hipofiz-gonad (HPG) aksına bağlı olmayan daha nadir görülen farklı bir durumdur ve periferik nedenlere bağlıdır. Metabolomiks, küçük molekül metabolitlerinin (

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Fabad Journal of Pharmaceutical Sciences Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science

CiteScore

0.80

自引率

0.00%

发文量

期刊介绍： The FABAD Journal of Pharmaceutical Sciences is published triannually by the Society of Pharmaceutical Sciences of Ankara (FABAD). All expressions of opinion and statements of supposed facts appearing in articles and/or advertisiments carried in this journal are published on the responsibility of the author and/or advertiser, anda re not to be regarded those of the Society of Pharmaceutical Sciences of Ankara. The manuscript submitted to the Journal has the requirement of not being published previously and has not been submitted elsewhere. Manuscripts should be prepared in accordance with the requirements specified as given in detail in the section of “Information for Authors”. The submission of the manuscript to the Journal is not a condition for acceptance; articles are accepted or rejected on merit alone. All rights reserved.