含谷氨酰胺的全肠外营养、含或不含谷氨酰胺的肠内液体治疗和液体治疗对剖腹手术后饥饿马的血脂图的影响

IF 0.4 4区 农林科学 Q4 VETERINARY SCIENCES
U.P. Melo, M.S. Palhares, C. Ferreira, F.O.P. Leme, V.A. Gheller
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引用次数: 0

摘要

摘要为了研究谷氨酰胺相关全肠外营养和谷氨酰胺相关或非谷氨酰胺相关肠内液体治疗对饥饿(第1阶段)和再喂养(第2阶段)马的血脂的影响,选取16匹4 ~ 14岁、平均体重248.40±2.28kg的健康成年杂交马,分为4个实验组,每组4只:用谷氨酰胺相关电解质进行肠内液治疗;PARGL组:谷氨酰胺相关的全肠外营养;ENTFL组:电解质肠内液治疗;PARFL组:肠外输液治疗。本研究分为两个阶段:第一阶段和第二阶段。根据该小组的说法,第一阶段包括进行剖腹探查和开始饥饿,以及给予治疗,而第二阶段包括重新喂养动物。在整个实验期间,该物种的总胆固醇值保持在正常范围内,但在第1阶段略有上升,随后在第2阶段下降。ENFL、ENTGL和PARFL组在第1期出现高甘油三酯血症是由于负能量平衡。提供含电解质和能量源的肠内液体治疗(含或不含谷氨酰胺)或肠外液体治疗对扭转负能量平衡的影响无效。因此,结合长期肠内或肠外液体治疗和食物剥夺的治疗方案需要额外的营养支持,以避免负能量平衡的有害影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effects of total parenteral nutrition associated with glutamine, enteral fluid therapy, with or without glutamine, and fluid therapy on the lipidogram of horses subjected to starvation after laparotomy
ABSTRACT In order to evaluate the effect of total parenteral nutrition associated with glutamine and enteral fluid therapy, associated or not with glutamine, on the lipidogram of horses subjected to starvation (phase 1) and refeeding (phase 2), 16 adult healthy horses were used, mixed breed, aged between four and fourteen years and average weight of 248.40 ± 2.28kg, divided into four experimental groups, with four animals per group: Group ENTGL: enteral fluid therapy with electrolytes associated with glutamine; Group PARGL: total parenteral nutrition associated with glutamine; Group ENTFL: enteral fluid therapy with electrolytes; and Group PARFL: parenteral fluid therapy. This study was divided into two phases: phase 1 and phase 2. Phase 1 consisted of performing exploratory laparotomy and beginning of starvation, in addition to the administration of treatments, according to the group, while phase 2 consisted of re-feeding the animals. Total cholesterol values remained within the normal range for the species throughout the experimental period, but there was a slight increase during phase 1, followed by a decrease in values in phase 2. Hypertriglyceridemia in the ENFL, ENTGL and PARFL groups during phase 1 occurred because of the negative energy balance. The provision of enteral fluid therapy with electrolytes and an energy source, with or without glutamine, or parenteral fluid therapy were not effective in reversing the effects of negative energy balance. Thus, therapeutic protocols that combine enteral or parenteral fluid therapy for prolonged periods and food deprivation need additional nutritional support to avoid the deleterious effects of negative energy balance.
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来源期刊
CiteScore
0.80
自引率
25.00%
发文量
111
审稿时长
9-18 weeks
期刊介绍: Publica artigos originais de pesquisa sobre temas de medicina veterinária, zootecnia, tecnologia e inspeção de produtos de origem animal e áreas afins relacionadas com a produção animal. Atualmente a revista mantém 628 permutas (419 internacionais e 209 nacionais), sendo um verdadeiro suporte para o recebimento de periódicos pela Biblioteca da Escola. A partir de 1999, a Escola de Veterinária delegou à FEP MVZ Editora o encargo do gerenciamento e edição de todas suas publicações, inclusive do Arquivo, ficando somente com o apoio logístico (instalações, equipamentos, pessoal etc.). O apoio financeiro é exercido pelo CNPq/FINEP e pela própria FEP MVZ.
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