评价使用不同水平锦葵提取物对西门塔尔小母牛皮肤损伤愈合的影响

IF 0.1 Q4 VETERINARY SCIENCES
Mehrdad Karimi, Pouya Parsaei, Shadman Shahzamani, Farhanaz Changaee
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引用次数: 0

摘要

为确定不同水平锦葵提取物对西门特小母牛皮肤二次损伤的影响,选取平均年龄、16月龄、平均体重270±45 kg (mean+SD)的40头西门特小母牛,评价不同水平锦葵提取物处理后皮肤病变的愈合情况。采用直径为2 cm的皮肤穿孔法,建立了西门塔尔小母牛实验性伤口切除模型。用生理盐水对照或用普通蓟和百里香提取物与羧甲基纤维素混合的煎液局部治疗18天。观察伤口的向心回缩,临床和组织学方面,直到完全愈合。在治疗的第一天,光疗剂呈现在百里香中,改善了牛皮肤皮损的愈合。这些处理有利于修复过程。存在于锦葵提取物中的植物治疗剂在炎症期和修复过程中显示出积极的作用。200毫克的锦葵提取物仅在治疗的第一天对母牛皮肤损伤的宏观方面显示出积极的影响。综上所述,不同水平锦葵提取物可改善西门塔尔小母牛的纤维增生,其热疗活性可用于局部治疗皮肤病变
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Evaluation the effect of use of different levels of mallow (Malva Sylvestris) derived extracts on cutaneous skin lesions healing in Simmental heifers
To determine the effect of different levels of mallow derived extracts on Simmental heifer’s cutaneous skin lesions by second intention, forty Simmental heifers by average age, 16 months and average weight of 270±45 kg (mean+SD) were selected to evaluate cutaneous lesions healing after treatment with different levels of mallow derived extracts. Experimental wound excision model in Simmental heifers was created by means of a skin punch of 2 cm diameter. The heifers were topically treated for 18 days with a saline control or decoctions of mixed with common thistle and thyme derived extracts with carboxymethyl cellulose. The centripetal retraction, clinical, and histological aspects of the wounds were observed until complete healing. The phototherapeutics agent presents in thyme improved cicatrization of cutaneous lesions in cattle skin during the first days of treatment. The treatments were beneficial to the reparation process. The phytotherapeutics agent present in mallow derived extracts showed positive effects in the inflammatory phase and on the reparation process. The mallow derived extracts at 200 mg showed a positive effect on the macroscopic aspect of cutaneous lesions in heifers only during the first treatment days. In conclusion different levels of mallow derived extracts improved fibroplasia and its pytotherapeutic activity may be useful in topical treatment of cutaneous lesions in Simmental heifers
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