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负载阿霉素的磷酸钙纳米颗粒对黑色素瘤细胞的抗增殖活性提高

IF 1 4区 生物学 Q3 BIOLOGY
Brazilian Archives of Biology and Technology Pub Date : 2023-01-01 DOI:10.1590/1678-4324-2023220572
Igor Barbosa Lima, Betania Mara Alvarenga, Priscila Izabel Santos de Tótaro, Fernanda Boratto, Elaine Amaral Leite, Pedro Pires Goulart Guimaraes
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引用次数: 1

摘要

N-Dox对A-375细胞的活性高于游离阿霉素。该制剂具有比游离阿霉素更高的选择性指标。处理引起衰老，短期暴露后没有菌落恢复。
本文章由计算机程序翻译，如有差异，请以英文原文为准。
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Improved Antiproliferative Activity of Doxorubicin-Loaded Calcium Phosphate Nanoparticles Against Melanoma Cells
HIGHLIGHTS N-Dox has higher activity against A-375 cells than free doxorubicin. The formulation has higher selectivity indices than free doxorubicin. Treatment induced senescence and no colonies recovered after short-term exposure.
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来源期刊
Brazilian Archives of Biology and Technology
Brazilian Archives of Biology and Technology 生物-生物学
CiteScore
1.80
自引率
0.00%
发文量
116
审稿时长
3 months
期刊介绍： Information not localized
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