Rutuja R Shah, Rahul S Adnaik, Pratibha R Adnaik, Swapnil S Patil
{"title":"秋葵黏液作为片剂粘结剂的提取、分离及特性研究","authors":"Rutuja R Shah, Rahul S Adnaik, Pratibha R Adnaik, Swapnil S Patil","doi":"10.52711/2231-5713.2023.00032","DOIUrl":null,"url":null,"abstract":"The major objective of the present investigation was to extract a natural polymer (okra mucilage) with its characterization as a pharmaceutical binder and to formulate, develop and evaluate the compression of tablet using okra binder. Binders are agent employed to impart cohesiveness to the granules. This ensures the tablet remain intact after compression. The researcher is trying to find new excipient for potential use of binding agent in tablet formulation continues to the interest. This is because different binding agent can be useful in achieving various tablet mechanical strength and drug release properties for different pharmaceutical purpose. The result presented here shows that the mucilage obtained from okra can be used as a binder in paracetamol tablets formulation with good physical properties. Tablet of long disintegration times were produced, hence it’s potential in binding and prepare the granule of pharmaceutical formulation.","PeriodicalId":8527,"journal":{"name":"Asian Journal of Pharmacy and Technology","volume":"76 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Extraction, Isolation and Characterization of Okra Mucilage, as Potential source of Binder in Tablet\",\"authors\":\"Rutuja R Shah, Rahul S Adnaik, Pratibha R Adnaik, Swapnil S Patil\",\"doi\":\"10.52711/2231-5713.2023.00032\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The major objective of the present investigation was to extract a natural polymer (okra mucilage) with its characterization as a pharmaceutical binder and to formulate, develop and evaluate the compression of tablet using okra binder. Binders are agent employed to impart cohesiveness to the granules. This ensures the tablet remain intact after compression. The researcher is trying to find new excipient for potential use of binding agent in tablet formulation continues to the interest. This is because different binding agent can be useful in achieving various tablet mechanical strength and drug release properties for different pharmaceutical purpose. The result presented here shows that the mucilage obtained from okra can be used as a binder in paracetamol tablets formulation with good physical properties. Tablet of long disintegration times were produced, hence it’s potential in binding and prepare the granule of pharmaceutical formulation.\",\"PeriodicalId\":8527,\"journal\":{\"name\":\"Asian Journal of Pharmacy and Technology\",\"volume\":\"76 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-08-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Asian Journal of Pharmacy and Technology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.52711/2231-5713.2023.00032\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Asian Journal of Pharmacy and Technology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.52711/2231-5713.2023.00032","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Extraction, Isolation and Characterization of Okra Mucilage, as Potential source of Binder in Tablet
The major objective of the present investigation was to extract a natural polymer (okra mucilage) with its characterization as a pharmaceutical binder and to formulate, develop and evaluate the compression of tablet using okra binder. Binders are agent employed to impart cohesiveness to the granules. This ensures the tablet remain intact after compression. The researcher is trying to find new excipient for potential use of binding agent in tablet formulation continues to the interest. This is because different binding agent can be useful in achieving various tablet mechanical strength and drug release properties for different pharmaceutical purpose. The result presented here shows that the mucilage obtained from okra can be used as a binder in paracetamol tablets formulation with good physical properties. Tablet of long disintegration times were produced, hence it’s potential in binding and prepare the granule of pharmaceutical formulation.