[从常规免疫抑制治疗转向环孢素A治疗肾移植术后并发症的结果]。

D Scholz, W Blank, C Bärwolf, G Ditscherlein, R Christenfeld, H Hüller
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引用次数: 0

摘要

41例肾移植术后出现并发症的患者,常规免疫抑制转为环孢素A,获得性免疫球蛋白G缺乏和持续白细胞减少的患者免疫抑制完全恢复正常。6例患有危及生命的细菌感染的患者在移植功能正常的同种异体移植物后存活下来,9例晚期排斥反应中有8例是可逆的。慢性肝病和慢性排斥反应可能需要转化。由于78%(46/59)接受者的并发症得到控制,建议改用环孢素A。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Results of conversion from conventional immunosuppressive therapy to cyclosporin A in complications following kidney transplantation].

In 41 patients suffering from complications late after kidney transplantation the conventional immunosuppression was converted to Cyclosporin A. A complete normalization was obtained in the case of acquired immunoglobulin G deficiency and in persistent leukocytopenia. 6 patients suffering from life-threatening bacterial infections did survive after conversion with functioning allograft and 8 out of 9 late rejections were reversible. Conversion may be necessary in chronic hepatopathy and chronic rejection. A conversion to cyclosporin A is recommended because of control of complications in 78% (46/59) of the recipients.

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