0.005%雌三醇阴道凝胶预防绝经后阴道萎缩妇女复发性尿路感染的疗效Blissure研究

Nuno Aquilino Muiños Fernández, José Ignacio Pardo González de Quevedo, Maria Pilar Diaz-Merino Martinez, Ildefonso Garcia Martin, Javier Rosado Martin, Maria Palma Santisteban, Eva Garcia Aguilar
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引用次数: 0

摘要

背景:绝经后雌激素水平下降导致阴道萎缩,导致pH升高,乳酸杆菌水平降低和生态失调,增加尿路感染(uti)的频率。局部雌激素可以恢复萎缩的阴道,刺激平衡菌群的增殖,预防泌尿系统症状。这种预防方法可以被认为是长期使用抗生素的替代方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Efficacy of a 0.005% estriol vaginal gel in preventing recurrent urinary tract infections in postmenopausal women with vaginal atrophy. Blissure study
Background: Decreased estrogen levels after menopause result in vaginal atrophy, leading to elevated pH, lower levels of Lactobacilli and dysbiosis, increasing the frequency of Urinary Tract Infections (UTIs). Topical estrogens restore the atrophic vagina stimulating the proliferation of a balanced flora and preventing urinary symptoms. This preventive approach can be considered an alternative to the use of long-term antibiotics.
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