腹腔镜结肠切除术对结肠癌有效吗?

IF 0.4 Q4 ONCOLOGY
Nasser Malekpour, Mohammad Hossein Ehsani, Samira Adhami, Sara Besharat
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引用次数: 0

摘要

背景:结肠癌是世界范围内最常见的胃肠道恶性肿瘤,占所有胃肠道肿瘤的一半以上,每年有超过100万新病例和50万死亡病例。目的:我们研究的目的是通过评估淋巴结来比较腹腔镜手术和开放手术在结肠癌手术中的效果。切除足够数量的淋巴结是至关重要的,因为更广泛的淋巴结切除与更高的生存率和更少的复发率有关。方法:本前瞻性研究纳入2019年至2021年在我科登记并分析的120例结肠癌患者(女性57例,男性63例)。在这些患者中,78人接受了开放手术,42人接受了腹腔镜手术。所有患者完成术后疼痛、住院时间、前30天部位感染、病理切除淋巴结数、血红蛋白下降、吻合口漏、尿路损伤、手术时间等8项指标的检查表。采用SPSS 21版软件进行数据分析,p值小于0.05为显著性。结果:患者年龄在30 ~ 60岁之间。前30天部位感染(P = 0.7)、吻合口漏并发症(P = 0.5)、尿路损伤(P = 0.02)、淋巴结清扫数(P = 0.13)两组间差异均无统计学意义。然而,运行时间变量(P <0.05),术后患者血红蛋白较术前降低(P <0.05),术后严重疼痛(P <0.05)、住院天数(P <腹腔镜手术组与开放手术组间差异有统计学意义(0.05)。结论:我们的经验表明,腹腔镜结肠切除术是一种安全可行的手术,具有较好的短期疗效和与开放入路相当的肿瘤疗效。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Does Laparoscopic Colectomy Work for Colon Cancer?
Background: Colon cancer is the most common gastrointestinal malignancy worldwide and accounts for more than half of all gastrointestinal tumors, with over 1 million new cases and 500 000 deaths per year. Objectives: The purpose of our study was to compare the outcomes of laparoscopic surgery and open surgery for colon cancer surgery by evaluating the lymph nodes. It is crucial to remove an adequate number of lymph nodes, as a more extensive nodal removal has been associated with higher survival rates and fewer relapses. Methods: This prospective study was conducted on 120 patients (57 females and 63 males) with colon cancer, who were registered and analyzed in our unit from 2019 to 2021. Of these patients, 78 underwent open surgery and 42 underwent laparoscopic surgery. A checklist comprising 8 variables including postoperative pain, length of hospital stay, site infection during the first 30 days, number of lymph nodes removed in pathology, hemoglobin drop, anastomotic leak, urinary tract injury, and time of operation was completed for all patients. SPSS version 21 software was used for data analysis, and a P-value less than 0.05 was considered significant. Results: The age of the patients was between 30 to 60 years. The variables of site infection during the first 30 days (P = 0.7), anastomotic leak complication (P = 0.5), urinary tract injury (P = 0.02), and number of lymph nodes removed (P = 0.13) were not statistically significant between the two groups of laparoscopic surgery and open surgery. However, the variables of duration of operation (P < 0.05), decrease in hemoglobin of postoperative patients compared to preoperative (P < 0.05), severe postoperative pain (P < 0.05), and number of days of hospital stay (P < 0.05) between the groups of laparoscopic surgery and open surgery were statistically significant. Conclusions: Our experience suggests that laparoscopic colectomy is a safe and feasible procedure with better short-term outcomes and comparable oncological efficacy to the open approach.
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来源期刊
CiteScore
1.10
自引率
0.00%
发文量
67
期刊介绍: International Journal of Cancer Management (IJCM) publishes peer-reviewed original studies and reviews on cancer etiology, epidemiology and risk factors, novel approach to cancer management including prevention, diagnosis, surgery, radiotherapy, medical oncology, and issues regarding cancer survivorship and palliative care. The scope spans the spectrum of cancer research from the laboratory to the clinic, with special emphasis on translational cancer research that bridge the laboratory and clinic. We also consider original case reports that expand clinical cancer knowledge and convey important best practice messages.
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