土耳其安塔利亚先天性巨细胞病毒感染病例及随访结果

IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL

Marmara Medical Journal Pub Date : 2023-09-29 DOI:10.5472/marumj.1367753

Zubeyde ERES SARITAS, Bilal Olcay PEKER, Dilek ÇOLAK, Imran SAGLIK, Rabia Can SARİNOĞLU, Murat TURHAN, Aslı BOSTANCI TOPTAŞ, Derya MUTLU, Gözde ÖNGÜT, Nihal OYGUR, Munire ERMAN

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引用次数: 0

摘要

目的:了解初诊新生儿cmmv感染及CMV-DNA病毒感染情况;筛查试验(NHST)和CMV-DNA病毒与cCMV患者身体、精神运动发育和听力状况的关系二岁。患者和方法:采用聚合酶链反应试剂盒和检测1150例新生儿口腔拭子(0-21天)CMV-DNA;唾液中CMV-DNA阳性患者的尿液。进行瞬态诱发耳声发射试验。结果:38例新生儿唾液CMV-DNA阳性(3.3%)，10例新生儿尿液CMV-DNA阳性。ccmv的流行为0.87% (95% CI=0.697-1.042)。所有新生儿都通过了NHST测试。cCMV新生儿:黄疸占60%(6/10)，低出生体重;40%(4/10)， 50%(5/10)小于胎龄。黄疸是最显著的变量(P

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Congenital cytomegalovirus infection cases and follow-up findings in Antalya, Turkey

Objective: To investigate the presence of cCMV infection and the CMV-DNA virus in the newborns who applied for newborn hearing screening test (NHST) and CMV-DNA viruria with physical, mental-motor development and hearing status of cCMV cases in the second year of age. Patients and Methods: CMV-DNA was investigated in 1150 newborns’ oral swabs (0-21 days) by polymerase chain reaction kit and urine of patients with positive CMV-DNA in saliva. Transient Evoked Otoacoustic Emission test was performed for NHST. Results: CMV-DNA was posititve in saliva of 38 (3.3%) newborns and urine of 10 out of 37 newborns. The prevalence of cCMV was 0.87% (95% CI=0.697-1.042). All newborns passed the NHST. In newborns with cCMV:jaundice in 60% (6/10), low birthweight in 40% (4/10), small for gestational age in 50% (5/10) of them. Jaundice was the most significant variable (P

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来源期刊

Marmara Medical Journal MEDICINE, GENERAL & INTERNAL-

CiteScore

0.30

自引率

0.00%

发文量

期刊介绍： Marmara Medical Journal, Marmara Üniversitesi Tıp Fakültesi tarafından yılda üç kere yayımlanan multidisipliner bir dergidir. Bu dergide tıbbın tüm alanlarına ait orijinal araştırma makaleleri, olgu sunumları ve derlemeler İngilizce veya Türkçe olarak yer alır.