Elissa Annabi, Sophie Lalevée, Thomas Bettuzzi, Juliette Demortier, Barbara Papouin, Louis De Mestier Du Bourg, Emilie Sbidian, Saskia Ingen-Housz-Oro
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Annular eruption with weight loss in a 47-year-old man
INTRODUCTION A 47yearold man, with no medical history, presented with a 1year history of a recurrent skin eruption made of erythematous, erosive, crusty and pruritic plaques involving the scrotum, inguinal and intergluteal skinfolds, trunk and legs (figure 1). Mucosal examination showed glossitis and perleche. He had received topical and systemic antifungal agents without improvement. General examination was normal except a weight loss of 9 kg, without other digestive symptoms and despite a balanced diet. Blood routine tests were normal except a mild normocytic anaemia (11 g/dL) and a hypoalbuminaemia (31 g/L). Nutritional assessment revealed a zinc deficiency (7.37 μmol/L, normal value >12.5 μmol/L). Histological examination of a skin biopsy revealed a psoriasiform acanthosis with a keratinocyte vacuolation.
期刊介绍:
Frontline Gastroenterology publishes articles that accelerate adoption of innovative and best practice in the fields of gastroenterology and hepatology. Frontline Gastroenterology is especially interested in articles on multidisciplinary research and care, focusing on both retrospective assessments of novel models of care as well as putative future directions of best practice. Specifically Frontline Gastroenterology publishes articles in the domains of clinical quality, patient experience, service provision and medical education.