{"title":"从系统药理学和分子对接研究附子、百芍治疗类风湿关节炎的作用机制","authors":"Yuxi Zhang, Haoming Zhou, Juan Liu, Dandan Zhang, Shijun Yue, Cheng Peng","doi":"10.14218/fim.2023.00044","DOIUrl":null,"url":null,"abstract":"Background and ObjectivesTraditional Chinese Medicine has been implemented in clinical practice for thousands of years to treat rheumatoid arthritis (RA). Aconitum carmichaelii Debx (Fuzi) and Paeonia lactiflora Pall (Baishao) are a common herb-pair that is used in many herbal prescriptions to treat RA. However, the mechanism of Fuzi and Baishao for treating RA remains unclear. Here, we used a systems pharmacology and molecular docking approach to investigate the mechanism of Fuzi and Baishao in the treatment of RA.","PeriodicalId":73126,"journal":{"name":"Future integrative medicine","volume":"48 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Uncovering the Mechanism of Fuzi and Baishao in Treating Rheumatoid Arthritis Using Systems Pharmacology and Molecular Docking\",\"authors\":\"Yuxi Zhang, Haoming Zhou, Juan Liu, Dandan Zhang, Shijun Yue, Cheng Peng\",\"doi\":\"10.14218/fim.2023.00044\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background and ObjectivesTraditional Chinese Medicine has been implemented in clinical practice for thousands of years to treat rheumatoid arthritis (RA). Aconitum carmichaelii Debx (Fuzi) and Paeonia lactiflora Pall (Baishao) are a common herb-pair that is used in many herbal prescriptions to treat RA. However, the mechanism of Fuzi and Baishao for treating RA remains unclear. Here, we used a systems pharmacology and molecular docking approach to investigate the mechanism of Fuzi and Baishao in the treatment of RA.\",\"PeriodicalId\":73126,\"journal\":{\"name\":\"Future integrative medicine\",\"volume\":\"48 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-09-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Future integrative medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.14218/fim.2023.00044\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Future integrative medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.14218/fim.2023.00044","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Uncovering the Mechanism of Fuzi and Baishao in Treating Rheumatoid Arthritis Using Systems Pharmacology and Molecular Docking
Background and ObjectivesTraditional Chinese Medicine has been implemented in clinical practice for thousands of years to treat rheumatoid arthritis (RA). Aconitum carmichaelii Debx (Fuzi) and Paeonia lactiflora Pall (Baishao) are a common herb-pair that is used in many herbal prescriptions to treat RA. However, the mechanism of Fuzi and Baishao for treating RA remains unclear. Here, we used a systems pharmacology and molecular docking approach to investigate the mechanism of Fuzi and Baishao in the treatment of RA.
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