卡前列素联合子宫带缝合治疗子宫张力不全所致产后出血的疗效观察

Hongying Liu, Hongmei Zhou
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摘要

目的:探讨和分析卡前列素联合子宫带缝合治疗子宫紧张性产后出血的效果。方法:选取2020年7月至2023年7月在达州市妇女儿童医院产科住院的90例因子宫张力所致产后出血患者作为研究对象。按奇数、偶数分组,分为手术组(n = 45)和药物组(n = 45)。手术组应用丙三胺卡前列素联合子宫带缝合,药物组应用丙三胺卡前列素。比较两组患者的总有效率、凝血指数、纤溶功能水平、出血量及血红蛋白变化。结果:手术组总有效率显著高于给药组(P <0.05)。治疗前,两组间凝血指标差异无统计学意义(P >0.05);治疗后,手术组凝血指标明显优于药物组(P <0.05)。治疗前,两组患者纤溶功能水平差异无统计学意义(P >0.05);治疗后,手术组纤溶功能水平明显优于药物组(P <0.05)。手术组2 h、24 h出血量及血红蛋白变化明显低于药物组(P <0.05)。结论:卡前列素联合带状缝合可有效控制子宫张力所致产后出血。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of Carboprost Tromethamine Combined with Uterine Strap Suture in the Treatment of Patients with Postpartum Hemorrhage Caused by Uterine Atony
Objective: To explore and analyze the effect of carboprost tromethamine combined with uterine strap suturein the treatment of postpartum hemorrhage caused by uterine atony. Methods: A total of 90 patients with postpartum hemorrhage due to uterine atony who were admitted to the Obstetrics Department of Dazhou Women and Children’s Hospital from July 2020 to July 2023 were included in the study. They were grouped by odd and even numbers, and divided into the surgery group (n = 45) and the drug group (n = 45). The surgery group was treated with carboprost tromethamine and uterine strap suture, and the drug group was treated with carboprost tromethamine. The total effective rate, blood coagulation index, fibrinolytic function level, bleeding, and hemoglobin changes were compared between the two groups. Results: The total effective rate of the surgery group was significantly higher than that of the medication group (P < 0.05). Before treatment, the blood coagulation indicators were insignificant between the groups (P > 0.05); after treatment, the blood coagulation indicators in the surgery group were significantly better than those in the drug group (P < 0.05). Before treatment, the levels of fibrinolytic functions were insignificant between the groups (P > 0.05); aftertreatment, the levels of fibrinolytic functions in the surgery group were significantly better than those in the drug group (P < 0.05). The 2 h and 24 h blood loss and hemoglobin changes in the surgery group were significantly lower than those in the drug group (P < 0.05). Conclusion: Carboprost tromethamine combined with strap sutures can effectively control postpartum hemorrhage caused by uterine atony.
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