[移植型横纹肌肉瘤小鼠局部白介素-2依赖性过继免疫细胞治疗的有效性评价]。

Eksperimental'naia onkologiia Pub Date : 1990-01-01

R A Semenova-Kobzar', V M Iudin, L Ia Kushko, L V Iakhimovich, N M Berezhnaia

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引用次数: 0

摘要

区域il -2依赖性过继免疫细胞治疗恶性肿瘤的替代原则提出。局部过继免疫细胞疗法包括在消除具有免疫抑制活性的细胞后，给予肿瘤切除的淋巴结中具有肿瘤相关抑制活性的淋巴细胞和脾脏细胞短期的IL-2处理。

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[Evaluation of the effectiveness of regional interleukin-2 dependent adoptive immunocytotherapy of mice with transplanted rhabdomyosarcoma].

Alternative principles of regional IL-2-dependent adoptive immunocytotherapy of malignant tumours are suggested. Regional adoptive immunocytotherapy consists in the administration of the short-term IL-2 treated lymphocytes of the lymph nodes removed from the tumour which have tumour-associated suppressor activity and spleen cells after elimination of cells with the immunosuppressive activity.

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Eksperimental'naia onkologiia

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