[阿霉素的急性血流动力学影响]。

Archiv fur Geschwulstforschung Pub Date : 1990-01-01
U Gerecke, B Katzberg
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引用次数: 0

摘要

几年前,一些作者报道了ADM的急性血流动力学作用。我们采用有创和无创两种方法对5例患者进行了研究,从而获得了最重要的血流动力学参数。急性血流动力学效应在负性肌力和血管舒张的意义被证实。常规静脉注射即使超过10分钟,也不能避免重要血流动力学参数(SV、SWI、CI)的降低。注射过程中可能发生的梗死和并发症可能是灌注压降低的结果,即“偷窃现象”。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Acute hemodynamic effects of adriamycin].

Several authors reported about acute haemodynamic effects of ADM years ago. We studied this problem in five patients in the invasive and noninvasive way and thus obtained the most important haemodynamic parameters. Acute haemodynamic effects in the meaning of a negative inotropy and vasodilatation are confirmed. The usual intravenous injection does not avoid the decrease of important haemodynamic parameters (SV, SWI, CI) even though injected over ten minutes. Possible infarction and complications during the injection may be the result of decrease of perfusion pressure in the meaning of a "steal phenomenon".

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