语言学研究的新领域:通过生物信息学消除理解语言遗传学的挑战

IF 0.7 3区 文学 0 HUMANITIES, MULTIDISCIPLINARY
Annuncy Vinoliya, Joseph Ponniah
{"title":"语言学研究的新领域:通过生物信息学消除理解语言遗传学的挑战","authors":"Annuncy Vinoliya, Joseph Ponniah","doi":"10.1093/llc/fqad040","DOIUrl":null,"url":null,"abstract":"Abstract The contemporary research in linguistics aims to forge an understanding of consilience by evading the stereotypic semantic studies in linguistics. Modern linguistics calls for understanding language evolution, language production, and language disorders in association with neuro-genetic studies. To undertake genetic trials, language scholars from the humanities and social sciences disciplines have constraints like funding, inaccessibility to genetic labs, and ethical issues over biological bodies. To resolve the constraints and to enhance extensive knowledge on the genetic association with language, this article employs bioinformatics tools, namely the Basic Local Alignment Search Tool (BLAST) and the Sorting Intolerant From Tolerant (SIFT). Through the BLAST tool, the article aids the language researcher to understand language evolution, and through the application of SIFT, the article highlights mutation points in the gene of a severe speech disorder. Finally, the article emphasizes the inclusion of bioinformatics in the field of humanities and social sciences with respect to language studies","PeriodicalId":45315,"journal":{"name":"Digital Scholarship in the Humanities","volume":null,"pages":null},"PeriodicalIF":0.7000,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"New frontiers in linguistic research: Eliminating the challenges of understanding the genetics of language through bioinformatics\",\"authors\":\"Annuncy Vinoliya, Joseph Ponniah\",\"doi\":\"10.1093/llc/fqad040\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Abstract The contemporary research in linguistics aims to forge an understanding of consilience by evading the stereotypic semantic studies in linguistics. Modern linguistics calls for understanding language evolution, language production, and language disorders in association with neuro-genetic studies. To undertake genetic trials, language scholars from the humanities and social sciences disciplines have constraints like funding, inaccessibility to genetic labs, and ethical issues over biological bodies. To resolve the constraints and to enhance extensive knowledge on the genetic association with language, this article employs bioinformatics tools, namely the Basic Local Alignment Search Tool (BLAST) and the Sorting Intolerant From Tolerant (SIFT). Through the BLAST tool, the article aids the language researcher to understand language evolution, and through the application of SIFT, the article highlights mutation points in the gene of a severe speech disorder. Finally, the article emphasizes the inclusion of bioinformatics in the field of humanities and social sciences with respect to language studies\",\"PeriodicalId\":45315,\"journal\":{\"name\":\"Digital Scholarship in the Humanities\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.7000,\"publicationDate\":\"2023-06-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Digital Scholarship in the Humanities\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1093/llc/fqad040\",\"RegionNum\":3,\"RegionCategory\":\"文学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"0\",\"JCRName\":\"HUMANITIES, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Digital Scholarship in the Humanities","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/llc/fqad040","RegionNum":3,"RegionCategory":"文学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"0","JCRName":"HUMANITIES, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0

摘要

当代语言学研究的目的是摆脱语言学中语义学研究的刻板印象,形成对顺应性的理解。现代语言学要求理解与神经遗传研究相关的语言进化、语言产生和语言障碍。为了进行基因试验,来自人文和社会科学学科的语言学者受到资金、无法进入基因实验室和生物身体伦理问题等方面的限制。为了解决这些限制并增强对语言遗传关联的广泛了解,本文采用了生物信息学工具,即基本局部比对搜索工具(BLAST)和不耐受从耐受排序工具(SIFT)。本文通过BLAST工具帮助语言研究者了解语言的进化,通过SIFT的应用,突出了一个严重语言障碍基因的突变点。最后,文章强调了将生物信息学纳入语言研究的人文社会科学领域
本文章由计算机程序翻译,如有差异,请以英文原文为准。
New frontiers in linguistic research: Eliminating the challenges of understanding the genetics of language through bioinformatics
Abstract The contemporary research in linguistics aims to forge an understanding of consilience by evading the stereotypic semantic studies in linguistics. Modern linguistics calls for understanding language evolution, language production, and language disorders in association with neuro-genetic studies. To undertake genetic trials, language scholars from the humanities and social sciences disciplines have constraints like funding, inaccessibility to genetic labs, and ethical issues over biological bodies. To resolve the constraints and to enhance extensive knowledge on the genetic association with language, this article employs bioinformatics tools, namely the Basic Local Alignment Search Tool (BLAST) and the Sorting Intolerant From Tolerant (SIFT). Through the BLAST tool, the article aids the language researcher to understand language evolution, and through the application of SIFT, the article highlights mutation points in the gene of a severe speech disorder. Finally, the article emphasizes the inclusion of bioinformatics in the field of humanities and social sciences with respect to language studies
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
1.80
自引率
25.00%
发文量
78
期刊介绍: DSH or Digital Scholarship in the Humanities is an international, peer reviewed journal which publishes original contributions on all aspects of digital scholarship in the Humanities including, but not limited to, the field of what is currently called the Digital Humanities. Long and short papers report on theoretical, methodological, experimental, and applied research and include results of research projects, descriptions and evaluations of tools, techniques, and methodologies, and reports on work in progress. DSH also publishes reviews of books and resources. Digital Scholarship in the Humanities was previously known as Literary and Linguistic Computing.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信