紫外激光足迹与dna -蛋白质交联

Conference Digest. 2000 International Quantum Electronics Conference (Cat. No.00TH8504) Pub Date : 2000-09-10 DOI:10.1109/IQEC.2000.908189

D. Angelov, S. Dimitrov, J. Cadet

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摘要

只提供摘要形式。蛋白质-核酸复合物是参与基因表达和调控控制过程的主要参与者。研究这些相互作用的直接而有力的方法是足迹和蛋白质- dna交联形成。蛋白质-DNA交联检测蛋白质在给定DNA序列上的存在，而足迹允许研究蛋白质-DNA相互作用的机制。

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UV laser footprinting and DNA-protein crosslinking

Summary form only given. Protein-nucleic acid complexes are the main players of the processes involved in the control of gene expression and regulation. Direct and powerful approaches for studying these interactions are footprinting and protein-DNA crosslinking formation. Protein-DNA crosslinking detects the presence of a protein on a given DNA sequence, while footprinting allows to study the mechanism of protein-DNA interactions.

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Conference Digest. 2000 International Quantum Electronics Conference (Cat. No.00TH8504)

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