[沙眼衣原体尿道炎患者氧氟沙星治疗前后尿道菌群的变化]。

IF 0.5 Q4 DERMATOLOGY

Przeglad dermatologiczny Pub Date : 1990-05-01

J Ruczkowska, I Dolna, I Choroszy-Król

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引用次数: 0

摘要

从40例患有CTU的男性尿道中分离出190株细菌，OFX(每日400 mg，连用5 d)治疗前110株，治疗后80株。在与沙眼衣原体共存的菌株中，表皮葡萄球菌(30.9%)、微球菌(13.6%)、D群链球菌(10.9%)和金黄色葡萄球菌(10.9%)的分离率最高。体外药敏试验显示，与红霉素、强力霉素、土霉素和复方新诺明相比，OFX对男性CTU患者尿道分离的大多数细菌(链球菌除外)的抗菌活性最高。发现OFX治疗可以减少分离菌株的总数，包括金黄色葡萄球菌和腐生葡萄球菌，而不会干扰正常的尿道菌群。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

本刊更多论文

[Bacterial flora in the urethra of men with Chlamydia trachomatis urethritis before and after treatment with ofloxacin].

From urethra of 40 men with CTU, 190 bacterial strains were isolated, 110 before and 80 after treatment with OFX (400 mg daily for 5 days). Among the strains coexisting with Chlamydia trachomatis, Staphylococcus epidermidis (30.9%), Micrococcus (13.6%), Streptococcus group D (10.9%) and Staphylococcus aureus (10.9%) were isolated more frequently than others. The in vitro susceptibility testing showed that, in comparison to erythromycin, doxycycline, oxytetracycline and co-trimoxazole, OFX was the most active antimicrobial agent against the majority of bacteria (except streptococci) isolated from urethra in CTU cases in men. The OFX treatment was found to reduce the total number of isolated strains, including Staphylococcus aureus and Staphylococcus saprophyticus, without disturbing normal urethral flora.

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来源期刊

Przeglad dermatologiczny DERMATOLOGY-

CiteScore

0.80

自引率

14.30%

发文量

审稿时长

12 weeks

期刊介绍： Przegląd Dermatologiczny (ang. Dermatological Review) is a bimonthly magazine of the Polish Dermatological Association. It publishes original (clinical and experimental) papers, review papers, care reports, reports from congresses, reviews of books, announcements, letters to the editor and special papers (requested by the editors), concerning selected dermatological and interdisciplinary issues. Papers sent to the editor are reviewed.