[促血管生成二肽对实验性慢性胃溃疡大鼠微循环的影响]。

Gastroenterologisches Journal : Organ der Gesellschaft fur Gastroenterologie der DDR Pub Date : 1990-01-01

W Brandt, D Modersohn, P Buntrock, B Johannsen, H Berndt

{"title":"[促血管生成二肽对实验性慢性胃溃疡大鼠微循环的影响]。","authors":"W Brandt, D Modersohn, P Buntrock, B Johannsen, H Berndt","doi":"","DOIUrl":null,"url":null,"abstract":"The influence of an angiogenesis stimulating dipeptide (Lys-Pro-derivative) on the blood flow rate of the stomach was tested in rats suffering from ulcus ventriculi by microspheres technique. 21 days after operation (acetic acid model by Takagi) the ulcers in the group treated with the dipeptide were healed completely, but not in the control group. The higher blood flow in the ulcer area of the dipeptide group radiometrically gained, was not changed significantly (U-test by Man-Whitney). These results demonstrate, that the process of rapid wound healing promoted by the dipeptide cannot entirely be explained by a higher blood flow of the stomach.","PeriodicalId":77539,"journal":{"name":"Gastroenterologisches Journal : Organ der Gesellschaft fur Gastroenterologie der DDR","volume":"50 2","pages":"88-90"},"PeriodicalIF":0.0000,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Effect of an angiogenesis-promoting dipeptide on microcirculation in experimental chronic stomach ulcer in the rat].\",\"authors\":\"W Brandt, D Modersohn, P Buntrock, B Johannsen, H Berndt\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The influence of an angiogenesis stimulating dipeptide (Lys-Pro-derivative) on the blood flow rate of the stomach was tested in rats suffering from ulcus ventriculi by microspheres technique. 21 days after operation (acetic acid model by Takagi) the ulcers in the group treated with the dipeptide were healed completely, but not in the control group. The higher blood flow in the ulcer area of the dipeptide group radiometrically gained, was not changed significantly (U-test by Man-Whitney). These results demonstrate, that the process of rapid wound healing promoted by the dipeptide cannot entirely be explained by a higher blood flow of the stomach.\",\"PeriodicalId\":77539,\"journal\":{\"name\":\"Gastroenterologisches Journal : Organ der Gesellschaft fur Gastroenterologie der DDR\",\"volume\":\"50 2\",\"pages\":\"88-90\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1990-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Gastroenterologisches Journal : Organ der Gesellschaft fur Gastroenterologie der DDR\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Gastroenterologisches Journal : Organ der Gesellschaft fur Gastroenterologie der DDR","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

用微球技术研究了促血管生成二肽(lys -原衍生物)对脑室沟大鼠胃血流速率的影响。术后21 d(高木醋酸模型)，二肽治疗组溃疡完全愈合，对照组溃疡未愈合。二肽组溃疡区血流量增高，但无明显变化(Man-Whitney u检验)。这些结果表明，二肽促进伤口快速愈合的过程不能完全用胃血流量增加来解释。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

本刊更多论文

[Effect of an angiogenesis-promoting dipeptide on microcirculation in experimental chronic stomach ulcer in the rat].

The influence of an angiogenesis stimulating dipeptide (Lys-Pro-derivative) on the blood flow rate of the stomach was tested in rats suffering from ulcus ventriculi by microspheres technique. 21 days after operation (acetic acid model by Takagi) the ulcers in the group treated with the dipeptide were healed completely, but not in the control group. The higher blood flow in the ulcer area of the dipeptide group radiometrically gained, was not changed significantly (U-test by Man-Whitney). These results demonstrate, that the process of rapid wound healing promoted by the dipeptide cannot entirely be explained by a higher blood flow of the stomach.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Gastroenterologisches Journal : Organ der Gesellschaft fur Gastroenterologie der DDR

自引率

0.00%

发文量