[用T淋巴细胞计数和B淋巴细胞计数评价实验性孢子虫病的免疫应答]。

Q4 Medicine

Medicina cutanea ibero-latino-americana Pub Date : 1990-01-01

R Ramos Zepeda, R Ramos Zepeda, M E Ramos Damian, B M González Rico, A González Mendoza

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引用次数: 0

摘要

免疫反应的效应细胞参与了细菌、病毒和真菌感染的临床过程。以前的出版物报道了一些真菌感染，包括孢子虫病，可以产生对宿主不利的免疫反应的负调节。本研究测定了沙鼠实验性孢子虫病的T淋巴细胞和B淋巴细胞分别与绵羊红细胞形成直接和间接的玫瑰花结。发现T淋巴细胞和B淋巴细胞的数量显著增加，这意味着正常的免疫反应。这些结果与孢子虫病可以抑制宿主免疫反应的观点不一致。

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[Evaluation of immune response in experimental sporotrichosis using T and B lymphocyte count].

The effector cells of the immune response are involved in the clinical course of bacterial, viral and mycotic infections. Previous publications have reported that some mycotic infections, including sporotrichosis, can produce a negative modulation of the immune response unfavorable for the host. In this work T and B lymphocytes capable to form direct and indirect rosettes respectively with sheep erythrocytes in gerbils with experimental sporotrichosis, were measured. It was found a significant rise in the number to T and B lymphocytes which means normal immunological reactivity. These results are not in accordance with the idea that sporotrichosis can depress the immune response of the host.

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来源期刊

Medicina cutanea ibero-latino-americana Medicine-Dermatology

自引率

0.00%

发文量

期刊介绍： La Revista Medicina Cutánea Ibero-Latino-Americana se adhiere a los “Requisitos de uniformidad para manuscritos presentados para publicación en revista biomédicas” elaborados por el Comité Internacional de Editores de Revista Médicas