R. Nasr, O. Falou, E. Hysi, L. Wirtzfeld, E. Berndl, Michael C. Kolios
{"title":"用平均散射体间距区分细胞化和去细胞化小鼠肾脏:初步研究","authors":"R. Nasr, O. Falou, E. Hysi, L. Wirtzfeld, E. Berndl, Michael C. Kolios","doi":"10.1109/MECBME.2016.7745422","DOIUrl":null,"url":null,"abstract":"Scattering from the extracellular matrix (ECM) is currently being investigated, using a decellularization technique, which involves removing cells from tissue while preserving the ECM. This work aims to investigate the use of the mean scatterer spacing, using cepstral analysis techniques, for the differentiation between cellularized and decellularized mouse kidneys. After decellularization, the mean scatterer spacing decreased, with an average spacing for all the kidneys of 5.97 ± 1.89 μm before decellularization, and 5.38 ± 1.72 μm after decellularization. A significant difference was found between the calculated spacings from the kidneys, before and after decellularization. Future work include the incorporation of other parameters to further improve the sensitivity of this technique.","PeriodicalId":430369,"journal":{"name":"2016 3rd Middle East Conference on Biomedical Engineering (MECBME)","volume":"51 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"Differentiation between cellularized and decellularized mouse kidneys using mean scatterer spacing: A preliminary study\",\"authors\":\"R. Nasr, O. Falou, E. Hysi, L. Wirtzfeld, E. Berndl, Michael C. Kolios\",\"doi\":\"10.1109/MECBME.2016.7745422\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Scattering from the extracellular matrix (ECM) is currently being investigated, using a decellularization technique, which involves removing cells from tissue while preserving the ECM. This work aims to investigate the use of the mean scatterer spacing, using cepstral analysis techniques, for the differentiation between cellularized and decellularized mouse kidneys. After decellularization, the mean scatterer spacing decreased, with an average spacing for all the kidneys of 5.97 ± 1.89 μm before decellularization, and 5.38 ± 1.72 μm after decellularization. A significant difference was found between the calculated spacings from the kidneys, before and after decellularization. Future work include the incorporation of other parameters to further improve the sensitivity of this technique.\",\"PeriodicalId\":430369,\"journal\":{\"name\":\"2016 3rd Middle East Conference on Biomedical Engineering (MECBME)\",\"volume\":\"51 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2016 3rd Middle East Conference on Biomedical Engineering (MECBME)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/MECBME.2016.7745422\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2016 3rd Middle East Conference on Biomedical Engineering (MECBME)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/MECBME.2016.7745422","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Differentiation between cellularized and decellularized mouse kidneys using mean scatterer spacing: A preliminary study
Scattering from the extracellular matrix (ECM) is currently being investigated, using a decellularization technique, which involves removing cells from tissue while preserving the ECM. This work aims to investigate the use of the mean scatterer spacing, using cepstral analysis techniques, for the differentiation between cellularized and decellularized mouse kidneys. After decellularization, the mean scatterer spacing decreased, with an average spacing for all the kidneys of 5.97 ± 1.89 μm before decellularization, and 5.38 ± 1.72 μm after decellularization. A significant difference was found between the calculated spacings from the kidneys, before and after decellularization. Future work include the incorporation of other parameters to further improve the sensitivity of this technique.
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