桨叶位置和尺寸对人经胸除颤的影响——三维有限元模型

M. Camacho, S. Eisenberg, N. Perlmutter, J. Lehr
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引用次数: 4

摘要

建立了人体胸腔导电解剖的三维有限元模型,以定量评估经胸除颤过程中心脏和胸腔内产生的电流密度分布。该模型基于一系列横断面CT扫描,并结合了8种组织的各向同性电导率和骨骼肌各向异性电导率的近似。测定了4对桨叶和2种桨叶尺寸的电流密度分布。我们的结果显示相当均匀的心肌电流密度分布为所有桨对和尺寸检查。最大电流密度值<使肌细胞失活所需的最小电流密度(Jlh)的4倍,表明临床常用的除颤桨位的安全系数至少为2.5。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Paddle position and size effects in human transthoracic defibrillation- a three-dimensional finite element model
A realistic three-dimensional (3D) finite element model (FEM) of the conductive anatomy of a human thorax has been constructed to quantitatively assess the current density distribution produced in the heart and thorax during transthoracic defibrillation. The model is based on a series of cross-sectional CT scans and incorporates isotropic conductivities for 8 tissues and an approximation of the anisotropic conductivity of skeletal muscle. Current density distributions were determined for 4 paddle pairings and 2 paddle sizes. Our results show fairly uniform myocardial current density distributions for all paddle pairs and sizes examined. Maximum current density values < 4 times the minimum current density (Jlh) necessary to inactivate a myocyte suggest that common clinically used defibrillation paddle positions have a safety factor of at least 2.5.
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