[原发性骨髓增生异常的染色体改变]。

Eksperimental'naia onkologiia Pub Date : 1990-01-01
L I Iavorkovskiĭ, L Iu Riauzova, E Ia Soloveĭ, L L Iavorkovskiĭ
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引用次数: 0

摘要

从文献资料的染色体异常在骨髓增生异常综合征的各个亚组(根据fab分类)提出。特别关注疾病期间染色体数量和结构变化的信息及其预后意义。明确的染色体畸变与疾病的临床病程和预后的关系,特别是与转变为急性白血病的关系正在讨论中。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Chromosomal changes in primary myelodysplasias].

The data from literature on chromosome abnormalities in various subgroups of the myelodysplastic syndrome (according to FAB-classification) are presented. Special attention is paid to information about changes in the number and structure of chromosomes during the disease and their prognostic significance. The relation of definite chromosome aberrations to the clinical course and prognosis of the disease, in particular to its transformation into acute leukosis is under discussion.

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