FRCA, FFICANZCA Ken Hillman (Director, Division of Critical Care), FANZCA, FFICANZCA Gillian Bishop (Director, Intensive Care Unit), FRACP Peter Bristow (Intensivist)
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1 The crystalloid versus colloid controversy: present status
The ‘crystalloid-colloid debate’ has a history clouded by practical issues of availability of colloids. The two kinds of solutions have different physical properties and different roles. While crystalloids can replete the circulation, they do so at the expense of a larger fluid load to the body which may have drawbacks.
Studies comparing mortality between the use of crystalloids and colloids have shown differing results. A definitive answer is unlikely from such studies. Early vigorous restoration of the circulation is more important.
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