Yield-Analysis of Different Coupling Schemes for Interconnected Bio-Reactors

Bio-chemical reaction networks are more and more adapted to be used for the production of fine chemicals. Due to the appearance of intermediate species which influence the single reaction steps, a single compartment approach for the implementation of such a reaction may not be optimal. Multi-compartment approaches however might have the potential to increase the yield of desired product if the coupling of the compartments is chosen appropriately. A model based approach is presented to identify and analyze such coupling schemes for a specific enzyme cascade as an example system.