不同生物统计学方法在生物数据分析中的应用

K. El-Bayomi, F. Mohamed, M. S. El-Tarabany, H. Gouda
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引用次数: 1

摘要

逻辑回归是遗传数据分析中常用的方法之一。它用于在预测变量的基础上预测分类二元因变量,并测试获得与解释变量相关的因变量的特定值的概率。本研究的目的是强调生物统计方法在提高兽医和生物实践结果准确性方面的关键作用。对埃及国家研究中心(National Research Center, Dokki, Giza, Cairo, Egypt)先前发表的数据进行统计分析,使用SPSS version, 24通过了解患者的基因型、年龄和性别来预测肝细胞癌转移。基因型和性别对转移有显著影响(p0.05)。还有其他类型的数据(动物育种和生产)通过重复测量方差分析和主成分分析(PCA)进行分析。重复测量方差分析等同于标准化方差分析,但针对相关组,而不是独立组。本试验数据来源于试验第4、6、8、10周4个时间点对3个品种家兔体重的测定。家兔品种类型的主效应显著(P < 1),值分别为(2.768和1.147)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Application of Different Biostatistical Methods in Biological Data Analysis
Logistic regression is one of the popular methods used in genetic data analysis. That is applied to predict a categorical binary dependent variable on basis of predictor variables, and to test the probability of getting a particular value of the dependent variable that is related to the explanatory variable. The objective of this study is to highlight the crucial role of biostatistical methods in increasing the accuracy of the results in veterinary and biological practices.  Statistical analysis of previously published data in the National Research Center, Dokki, Giza, Cairo, Egypt was done using SPSS version, 24 to predict hepatocellular carcinoma metastasis by knowing the genotypes, age, and gender of the patients. The genotypes and gender displayed a significant effect on metastasis (P 0.05). There are other types of data (animal breeding and production) which were analyzed by repeated measures ANOVA and principal component analysis (PCA). The repeated measures ANOVA is equivalent to normalized ANOVA, but for related, not independent groups. Data of this test was obtained from a study aimed to measure body weight of three breeds of rabbits at 4 time points 4th, 6th, 8th and 10th weeks of the experiment. The main effect of breed types of rabbits was significant (P 1 for two variables and their values were (2.768 and 1.147).
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