2.2金属/生物催化剂双重催化

Dual Catalysis in Organic Synthesis 2 Pub Date : 1900-01-01 DOI:10.1055/sos-sd-232-00083

M. Diéguez, J. Bäckvall, O. Pàmies

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摘要

化学酶动态动力学分解(DKR)和动态动力学不对称转化(DYKAT)过程已成为制备手性分子最具吸引力的转化方法。本文综述了金属外消旋化催化剂与生物催化剂结合合成对映纯醇类、胺类及其他相关化合物的研究进展。

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2.2 Metal/Biocatalyst Dual Catalysis

Chemoenzymatic dynamic kinetic resolution (DKR) and dynamic kinetic asymmetric transformation (DYKAT) processes have become some of the most appealing transformations for the preparation of chiral molecules. In this review, we present the huge advances made in the combination of a metal racemization catalyst and a biocatalyst for the synthesis of enantiopure alcohols, amines, and other relevant compounds.

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Dual Catalysis in Organic Synthesis 2

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