[低敏性免疫治疗患者皮下结节和对铝的敏感性]。

Q4 Medicine

Medicina cutanea ibero-latino-americana Pub Date : 1990-01-01

V García-Patos, A Alomar, R Lleonart, A Cistero, X Matias-Guiu

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引用次数: 0

摘要

对铝的过敏反应非常普遍。据报道，在持续使用含铝止汗剂或在疫苗和低敏免疫疗法中使用铝佐剂时，会发生致敏。我们报告了5例在免疫治疗后出现持续瘙痒的皮下结节的患者。组织学上，结节表现为肉芽肿反应，与铝的迟发性超敏反应一致。3名患者用2%氯化铝水溶液进行斑贴试验呈阳性，用其他金属(镍、钴)进行斑贴试验也经常出现阳性结果。

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[Subcutaneous nodules and sensitivity to aluminum in patients undergoing hyposensitivity immunotherapy].

Hypersensitivity reactions to aluminium are very rate. Sensitization has been reported to occur during continuous application of aluminium-containing antiperspirants or by aluminium adjuvants in vaccines and hyposensitization immunotherapy. We report 5 patients who developed persistent and itching subcutaneous nodules following immunotherapy. Histologically, the nodules showed a granulomatous reaction consistent with delayed hypersensitivity to aluminium. Patch tests with 2% aluminium chloride in water were positive in three patients, and positive results of patch test with other metals (nickel, cobalt) were frequently associated.

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来源期刊

Medicina cutanea ibero-latino-americana Medicine-Dermatology

自引率

0.00%

发文量

期刊介绍： La Revista Medicina Cutánea Ibero-Latino-Americana se adhiere a los “Requisitos de uniformidad para manuscritos presentados para publicación en revista biomédicas” elaborados por el Comité Internacional de Editores de Revista Médicas