药物占有比法对代谢综合征患者治疗依从性的影响

C. Setiawan, Phebe Hendra, D. Virginia, L. K. Sari
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摘要

代谢综合征在发展中国家仍然是一个主要问题,它与高血压、血糖和血脂异常有关,而这些异常会导致心血管疾病。这表明提供充分的治疗是重要的,但患者的依从性对结果有影响。提高患者对治疗的依从性可以更好地控制病情。因此,本研究旨在确定药物依从性与代谢综合征治疗结果之间的关系。本观察性分析研究采用回顾性队列设计,观察期为1年,即2020年4月至2021年3月。采用药物占有比法评估患者依从性对血压、血糖和血脂等治疗结果的影响。这项研究是通过检查Bethesda Lempuyangwangi医院的患者医疗记录作为依从性参数进行的,同时由专家评估结果参数。对获得的数据采用方差分析(均质数据)或Kruskal-Wallis(非均质数据)进行分析,以确定基于患者特征的依从性差异。使用logistic双变量分析依从性与治疗结果的关系。在观察到的174例患者数据中,只有151例进行了血液检查。平均收缩压、总胆固醇、甘油三酯和HbA1c水平均高于标准阈值。三个依从性水平与血压、糖化血红蛋白和血脂无显著关系(p>0.05)。调整后的年龄和性别依从性数据显示,患者依从性较低,甘油三酯水平高的风险是其他患者的2.08倍(p<0.05)。结果表明患者对治疗的依从性较低,因此卫生专业人员必须加强教育以改善这种情况。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Influence of Therapy Compliance Using Medication Possession Ratio Method for Patients with Metabolic Syndrome
Metabolic syndrome is still a major problem in developing countries and it has an association with high blood pressure, blood glucose, and lipid profile abnormalities, which can cause cardiovascular disease. This indicates that it is important to provide adequate treatment, but patient compliance has effects on the outcome. Improving patients’ compliance to treatment can provide a better control of the condition. Therefore, this study aimed to determine the association between medication compliance and the therapeutic outcome of metabolic syndrome. This observational analytic study was conducted using a retrospective cohort design for one year of observation, namely April 2020-March 2021. The influence of patient compliance with therapy outcomes in terms of blood pressure, blood glucose, and lipid profile was assessed using the medication possession ratio method. This study was carried out by examining patients’ medical records from the Bethesda Lempuyangwangi Hospital as parameters for compliance, while the outcome parameters were assessed by experts. The data obtained were analyzed using Anova (homogeneous data) or Kruskal-Wallis (not homogeneous data) to determine the differences in the compliance based on patients’ characteristics. The relationship of adherence to therapeutic outcomes was analyzed using logistic bivariate. From 174 patients’ data that was observed, only 151 had a blood test. The average systolic blood pressure, total cholesterol, triglyceride, and HbA1c levels were above the standard threshold. The three levels of compliance had no significant relationship with blood pressure, HbA1c, and lipid profiles (p>0.05). The adjusted data for age and gender on adherence showed patients with low compliance, and they have a 2.08 times risk of having high triglyceride levels compared to others (p<0.05). The results indicated the patients’ low compliance to therapy, hence, health professionals must strengthen education to improve this condition.
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