第四章。药物发现中的流动化学

Green Chemistry Series Pub Date : 2019-06-27 DOI:10.1039/9781788016131-00053

J. Alcázar, A. Hoz, Á. Díaz‐Ortiz

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引用次数: 3

摘要

本章概述了流动化学在药物发现中的应用，首先介绍了流动化学的绿色特征，然后描述了药物发现过程以及如何将这两个世界相匹配。所提供的例子涵盖了药物发现的所有阶段，从初始命中的识别到活性药物成分的制备。此外，还报道了新的绿色技术的自动化和集成。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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CHAPTER 4. Flow Chemistry in Drug Discovery

This chapter provides an overview of the use of flow chemistry in drug discovery settings, first introducing the green characteristics of flow chemistry and then describing the drug discovery process and how both worlds can be matched. Examples are provided that cover all stages of drug discovery, from the identification of the initial hits to the preparation of Active Pharmaceutical Ingredients. The automation and integration of new green technologies are also reported.

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Green Chemistry Series

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