{"title":"一种新型护肤霜对正己烷、三氯乙烯和甲苯等有机溶剂刺激皮肤的实验研究。","authors":"J M Lachapelle, H Nouaigui, L Marot","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>In a first experiment, the potential effectiveness of three cream formulations (A, B, C) against skin irritation due to n-hexane was evaluated using a guinea pig model. Semi-quantitative histopathological assessment of skin lesions were carried out. Due to interesting protective effects, cream formulation A (Travabon) was selected and further investigated. In a second series of experiments, this cream showed some protective effects against irritation due to toluene, but was not found efficacious against trichlorethylene irritation.</p>","PeriodicalId":11073,"journal":{"name":"Dermatosen in Beruf und Umwelt. Occupation and environment","volume":"38 1","pages":"19-23"},"PeriodicalIF":0.0000,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Experimental study of the effects of a new protective cream against skin irritation provoked by the organic solvents n-hexane, trichlorethylene and toluene.\",\"authors\":\"J M Lachapelle, H Nouaigui, L Marot\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>In a first experiment, the potential effectiveness of three cream formulations (A, B, C) against skin irritation due to n-hexane was evaluated using a guinea pig model. Semi-quantitative histopathological assessment of skin lesions were carried out. Due to interesting protective effects, cream formulation A (Travabon) was selected and further investigated. In a second series of experiments, this cream showed some protective effects against irritation due to toluene, but was not found efficacious against trichlorethylene irritation.</p>\",\"PeriodicalId\":11073,\"journal\":{\"name\":\"Dermatosen in Beruf und Umwelt. Occupation and environment\",\"volume\":\"38 1\",\"pages\":\"19-23\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1990-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Dermatosen in Beruf und Umwelt. Occupation and environment\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Dermatosen in Beruf und Umwelt. Occupation and environment","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Experimental study of the effects of a new protective cream against skin irritation provoked by the organic solvents n-hexane, trichlorethylene and toluene.
In a first experiment, the potential effectiveness of three cream formulations (A, B, C) against skin irritation due to n-hexane was evaluated using a guinea pig model. Semi-quantitative histopathological assessment of skin lesions were carried out. Due to interesting protective effects, cream formulation A (Travabon) was selected and further investigated. In a second series of experiments, this cream showed some protective effects against irritation due to toluene, but was not found efficacious against trichlorethylene irritation.
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