遗传毒性研究结果的统计分析。

W Szymczak, B Przybojewska
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引用次数: 0

摘要

体内微核试验是化合物遗传毒性研究中常用的方法之一。至于哪种统计方法最适合研究微核多染红细胞的发生频率,目前还没有明确的共识。本文提出了两种统计检验:近似正态检验和条件二项检验(Kastenbaum & Bowman)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Statistical analysis of the genotoxicity study results.

One of the methods used in the genotoxicity study of chemical compounds is micronucleus test in vivo. There is no clear consensus as to which statistical method is most suitable to study the frequency of occurrence of micronucleated polychromatic erythrocytes. This paper proposes two statistical tests: approximate normal test and conditional binomial test (Kastenbaum & Bowman).

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