基于心脏和循环数值模型的闭环自适应心率起搏仿真

Proceedings of 16th Annual International Conference of the IEEE Engineering in Medicine and Biology Society Pub Date : 1994-11-03 DOI:10.1109/IEMBS.1994.412109

M. Schaldach, A. Urbaszek, H. Hutten

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引用次数: 1

摘要

建立了人类心血管系统的数值模型，研究心脏的变时性和变肌力反应以及外周对变化的代谢需求的适应。自主神经系统(ANS)控制涵盖了模型的所有三个层面:循环、心脏力学和心肌细胞。模拟的目的是研究速率响应性起搏的控制方面，并开发和测试基于心脏控制信号的速率适应算法，其中单极心内阻抗测量是特别感兴趣的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Simulation of closed-loop rate-adaptive pacing with a numerical heart and circulation model

A numerical model of the human cardiovascular system was developed to study the chronotropic and inotropic responses of the heart as well as peripheral adaptation to changing metabolic demands. Autonomic nervous system (ANS) control covers all three levels of the model: circulation, heart mechanics and myocardial cell. The purpose of the simulations is to investigate the control aspects of rate responsive pacing and to develop and test algorithms for rate adaptation based on cardiac control signals, of which unipolar intracardiac impedance measurements are of special interest.<>

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Proceedings of 16th Annual International Conference of the IEEE Engineering in Medicine and Biology Society

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