[内外用皮质激素治疗]。

Zeitschrift fur Hautkrankheiten Pub Date : 1990-06-01
J Pichl, H Schell
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引用次数: 0

摘要

皮质激素的毒理学、药理学和临床特性已被充分了解。由于它们的主要作用是基于一种统一的机制,因此不可能将有益的效果与副作用分开。因此,任何治疗活性的增强都与全身和局部使用的副作用风险增加有关。局部应用强效皮质激素也有全身副作用的风险,特别是那些长期有效的。此外,必须记住,除皮肤外,全身使用皮质激素时,各种器官的功能也会受到不利影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Internal and external therapy with corticoids].

The toxicological, pharmacological, and clinical properties of corticoids are well understood. As their main actions are based on an uniform mechanism, it is impossible to separate beneficial effects from side effects. Therefore, any augmentation of the therapeutic activity is associated with an increased risk of side effects in systemic as well as in topical use. The topical application of highly potent corticoids also bears the risk of systemic side effects, especially those with prolonged activity. In addition, it has to be kept in mind that apart from the skin, the functions of various organs can be unfavorably affected when corticoids are systemically applied.

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