Ivan Raška , Robert L. Ochs , Lauree Salamin-Michel
{"title":"细胞核的免疫细胞化学","authors":"Ivan Raška , Robert L. Ochs , Lauree Salamin-Michel","doi":"10.1016/0892-0354(90)90006-E","DOIUrl":null,"url":null,"abstract":"<div><p>This electron microscopic review addresses <em>in situ</em> immunocytochemistry of the mammalian cell nucleus with special reference to the use of autoantibodies, which are the major source of antinuclear antibodies. The localization of many key nuclear antigens is documented and immunocytochemical data are related to the major functional processes of transcription and processing of RNA and to replication of DNA.</p></div>","PeriodicalId":77112,"journal":{"name":"Electron microscopy reviews","volume":"3 2","pages":"Pages 301-353"},"PeriodicalIF":0.0000,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0892-0354(90)90006-E","citationCount":"72","resultStr":"{\"title\":\"Immunocytochemistry of the cell nucleus\",\"authors\":\"Ivan Raška , Robert L. Ochs , Lauree Salamin-Michel\",\"doi\":\"10.1016/0892-0354(90)90006-E\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>This electron microscopic review addresses <em>in situ</em> immunocytochemistry of the mammalian cell nucleus with special reference to the use of autoantibodies, which are the major source of antinuclear antibodies. The localization of many key nuclear antigens is documented and immunocytochemical data are related to the major functional processes of transcription and processing of RNA and to replication of DNA.</p></div>\",\"PeriodicalId\":77112,\"journal\":{\"name\":\"Electron microscopy reviews\",\"volume\":\"3 2\",\"pages\":\"Pages 301-353\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1990-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/0892-0354(90)90006-E\",\"citationCount\":\"72\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Electron microscopy reviews\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/089203549090006E\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Electron microscopy reviews","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/089203549090006E","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
This electron microscopic review addresses in situ immunocytochemistry of the mammalian cell nucleus with special reference to the use of autoantibodies, which are the major source of antinuclear antibodies. The localization of many key nuclear antigens is documented and immunocytochemical data are related to the major functional processes of transcription and processing of RNA and to replication of DNA.