扁桃体窝局部浸润布比卡因与地塞米松对扁桃体切除术后发病率的比较分析

Kommineni Aruna, P. S. Sukthankar, P. Raga
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摘要

背景:扁桃体切除术是儿童耳鼻喉科最常见的手术之一。疼痛和呕吐是手术后常见的并发症。目的:比较布比卡因与地塞米松在扁桃体窝浸润治疗术后疼痛和呕吐的疗效。方法:共纳入100例慢性扁桃体炎患者,年龄10-30岁,男女均可。分为A、B两组,A组局部浸润0.5%布比卡因(1mg/kg体重),B组扁桃体床局部浸润地塞米松(0.15mg/kg体重)。所有患者均采用解剖/圈套技术切除扁桃体,通过局部加压和结扎控制出血,从而避免烧灼。扁桃体切除术后疼痛以视觉模拟量表(VAS)评估,恶心呕吐以缺席/存在进行比较。结果:布比卡因组(A)术后1小时86%的患者镇痛效果明显,6小时全部完全镇痛。地塞米松组(B)所有患者的镇痛作用在12小时和48小时开始(p<0.001)。布比卡因组(A)术后恶心呕吐发生率分别为76%和30%。地塞米松组(B)恶心呕吐发生率分别为10%。结论:我们的研究表明,0.5%布比卡因与地塞米松相比可显著减轻术后即时疼痛,地塞米松与0.5%布比卡因相比可显著减轻术后恶心和呕吐。两组均未出现因额外手术干预而引起的不良反应或并发症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparative analysis of local infiltration of tonsillar fossa with bupivacaine versus dexamethasone on post tonsillectomy morbidity
Background: Tonsillectomy is one of the most common surgery performed in pediatric otorhinolaryngology. Pain and vomiting being the usual morbidity following this surgery. Aim & Objective: To compare the efficacy of infiltration of Bupivacaine versus dexamethasone into the tonsillar fossa in postoperative pain and vomiting. Methods: A total of 100 patients, aged 10-30 years of both sexes with chronic tonsillitis accrued into the study. They were divided in to two groups A and B. Group A was infiltrated with 0.5% bupivacaine (1mg/kg body weight) locally and Group B with dexamethasone (0.15mg/kg bodyweight) locally into the tonsillar bed. All patients underwent tonsillectomy by dissection/snare technique, bleeding was controlled by applying local pressure, and by ligatures, thereby avoiding cauterization. Post tonsillectomy pain assessed by visual analog scale (VAS), nausea and vomiting by absence/presence was compared between both groups. Results: In Bupivacaine group (A), 86% patients observed analgesic effect by the 1 postoperative hour and by 6 hour all had complete analgesia. In dexamethasone group (B) the analgesic effect started by 12hour and by 48 hour in all patients (p<0.001). Post-operative occurrence of nausea and vomiting in bupivacaine group (A) was 76% and 30% respectively. However, in dexamethasone group (B), the nausea and vomiting was observed in 10% respectively. Conclusion: Our study showed that 0.5% bupivacaine reduces immediate post-operative pain significantly as compared to dexamethasone and dexamethasone reduces postoperative nausea and vomiting significantly as compared to 0.5% bupivacaine. There were no adverse reactions or complications due to the additional surgical intervention in both the groups.
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