{"title":"方法采用反相高效液相色谱法对复方拉坦前列素进行开发和验证","authors":"K.Srinivas, D.Narendra, P.V.V.Varaprasad, G.Jaya durga madhuri, K.Eswari, N.Shanti priya","doi":"10.47070/ijraps.v7i4.142","DOIUrl":null,"url":null,"abstract":"Chromatography was performed with a mobile phase containing a methanol of assay (99.8%) with flow rate of 1ml/min. Quantitation was accomplished with an internal standard method. The procedure was validated for linearity (correlation coefficient = 0.990), accuracy and Limit of detection (LOD) intraday precision. To test validation of the Latanoprost three factors were considered as linearity, precision, LOD where mobile phase, flowrate and pressure are respectively selected as methanol, 1 ml/min, 1600 pascals.","PeriodicalId":218317,"journal":{"name":"International Journal of Research in AYUSH and Pharmaceutical Sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Method Development and Validation of Latanoprost by using RP-HPLC in Pharmaceutical Formulations\",\"authors\":\"K.Srinivas, D.Narendra, P.V.V.Varaprasad, G.Jaya durga madhuri, K.Eswari, N.Shanti priya\",\"doi\":\"10.47070/ijraps.v7i4.142\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Chromatography was performed with a mobile phase containing a methanol of assay (99.8%) with flow rate of 1ml/min. Quantitation was accomplished with an internal standard method. The procedure was validated for linearity (correlation coefficient = 0.990), accuracy and Limit of detection (LOD) intraday precision. To test validation of the Latanoprost three factors were considered as linearity, precision, LOD where mobile phase, flowrate and pressure are respectively selected as methanol, 1 ml/min, 1600 pascals.\",\"PeriodicalId\":218317,\"journal\":{\"name\":\"International Journal of Research in AYUSH and Pharmaceutical Sciences\",\"volume\":\"1 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-04-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Research in AYUSH and Pharmaceutical Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.47070/ijraps.v7i4.142\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Research in AYUSH and Pharmaceutical Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.47070/ijraps.v7i4.142","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Method Development and Validation of Latanoprost by using RP-HPLC in Pharmaceutical Formulations
Chromatography was performed with a mobile phase containing a methanol of assay (99.8%) with flow rate of 1ml/min. Quantitation was accomplished with an internal standard method. The procedure was validated for linearity (correlation coefficient = 0.990), accuracy and Limit of detection (LOD) intraday precision. To test validation of the Latanoprost three factors were considered as linearity, precision, LOD where mobile phase, flowrate and pressure are respectively selected as methanol, 1 ml/min, 1600 pascals.
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