免疫荧光法测定ca19 -9和ca125。

Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie Pub Date : 1990-12-01 DOI:10.1515/cclm.1990.28.12.919

M Plebani, D Faggian, M Masiero, A Giacomini, A Burlina

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引用次数: 5

摘要

我们评估了一种新的免疫荧光技术(ILMA)用于检测血清中癌症抗原CA 19-9和CA 125。重复性良好，运行内和运行间的变异系数为4.2 ~ 7.3%。在较宽的浓度范围内，试验保持线性。ca19 -9的平均分析回收率为94%，ca125为98%。免疫放射测定结果与评估方法之间的显著一致性发现CA 125 (ILMA = 0.917 IRMA + 1.048;R = 0.966;n = 98)和CA 19-9 (ILMA = 1.156 IRMA + 0.996;R = 0.995;N = 100)。

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CA 19-9 and CA 125 determination by immunoluminometric assay.

We evaluated a new immunoluminometric technique (ILMA) for the measurement of the cancer antigens, CA 19-9 and CA 125 in serum. A satisfactory reproducibility was found, coefficients of variation ranging from 4.2 to 7.3% in within-run and between-run assays. The linearity of tests was maintained over a wide concentration range. Mean analytical recovery was 94% for CA 19-9 and 98% for CA 125. A significant agreement between results obtained by immunoradiometric assays and evaluated methods was found both for CA 125 (ILMA = 0.917 IRMA + 1.048; r = 0.966; n = 98) and CA 19-9 (ILMA = 1.156 IRMA + 0.996; r = 0.995; n = 100).

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Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie

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